BIRC8 Products

Antibodies
BIRC8 Antibody
BIRC8 Antibody
NB100-55770
Species: Hu, Mu, Rt
Applications: WB
Host: Rabbit Polyclonal
BIRC8 Antibody
BIRC8 Antibody
NBP1-76669
Species: Hu, Mu, Rt
Applications: WB, ELISA, ICC/IF
Host: Rabbit Polyclonal
BIRC8 Antibody
BIRC8 Antibody
NBP1-03071
Species: Hu, Mu, Rt
Applications: WB, ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
Lysates
BIRC8 Overexpression Lysate ( ...
BIRC8 Overexpression Lysate (Denat...
H00112401-T01
Species: Hu
Applications: WB
BIRC8 Overexpression Lysate ( ...
BIRC8 Overexpression Lysate (Native)
NBP2-05890
Applications: WB
Proteins
BIRC8 Recombinant Protein
BIRC8 Recombinant Protein
H00112401-P01
Species: Hu
Applications: WB, ELISA, PA
BIRC8 Partial Recombinant Pro ...
BIRC8 Partial Recombinant Protein
H00112401-Q01
Species: Hu
Applications: WB, ELISA, PA
BIRC8 Peptide
BIRC8 Peptide
NBP1-76669PEP
Species: Hu
Applications: AC
RNAi
BIRC8 RNAi
BIRC8 RNAi
H00112401-R01
Species: Hu

Description

Apoptosis, or programmed cell death, is related to many diseases, such as cancer. Apoptosis is triggered by a variety of stimuli including members in the TNF family and prevented by the inhibitor of apoptosis (IAP) proteins. IAP proteins form a conserved gene family including IAP, XIAP/ILP-1/MIHA, and Livin/KIAP that bind to and inhibits specific proteases. A novel member in the IAP protein family was recently identified and designated ILP-2 for IAP-like protein-2. ILP-2 has high homology to ILP-1, but is encoded by a distinct gene that is solely expressed in testis of tested normal human tissues. ILP-2, unlike ILP-1, has no inhibitory effect on Fas and TNF induced apoptosis, but potently inhibits apoptosis induced by overexpression of Bax or by coexpression of caspase-9 with Apaf-1. ILP-2 interacts with the processed caspase-9. These results suggest that ILP-2 is a novel IAP family member with restricted specificity for caspase-9.

Bioinformatics

Entrez Human
Uniprot Human
Human
Human
Human
Product By Gene ID 112401
Alternate Names
  • Inhibitor of apoptosis-like protein 2
  • baculoviral IAP repeat-containing protein 8
  • hILP2
  • IAP-like protein 2
  • baculoviral IAP repeat-containing 8
  • ILP-2ILP2
  • Testis-specific inhibitor of apoptosis
  • baculoviral IAP repeat containing 8

Pathways for BIRC8

View related products by pathway and learn more about each of the pathways below.

Cell Death
Cell Division
Programmed Cell Death
Induction Of Apoptosis
Tissue Homeostasis
Oncogenesis

Research Areas for BIRC8

Find related products by research area and learn more about each of the different research areas below.

Apoptosis
Cancer
Tumor Suppressors
Zinc Finger

Bioinformatics Tool for BIRC8

Discover related pathways, diseases and genes to BIRC8. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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