BIRC6 Antibody

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Product Details

Summary
Reactivity Hu, Mu, Rt, BvSpecies Glossary
Applications ICC/IF, PEP-ELISA
Clonality
Polyclonal
Host
Goat
Conjugate
Unconjugated
Concentration
0.5 mg/ml

Order Details

BIRC6 Antibody Summary

Immunogen
Peptide with sequence C-SREYDGNIRQAT corresponding to internal region according to NP_057336.3.
Epitope
C-SREYDGNIRQAT
Isotype
IgG
Clonality
Polyclonal
Host
Goat
Gene
BIRC6
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunocytochemistry/Immunofluorescence 1:10 - 1:500
  • Peptide ELISA Detection limit 1:64000
Application Notes
WB: Preliminary experiments gave bands at approx. 90 kDa band and 70 kDa band in A431 and HeLa lysates after 0.1 ug/ml antibody staining. Please note that currently we cannot find an explanation in the literature for the bands we observe given the calculated size of 530 kDa band according to NP_057336.3. Both detected bands were successfully blocked by incubation with the immunizing peptide (and BLAST results with the immunizing peptide sequence did not identify any other proteins to explain the additional bands).
Publications
Read Publication using NBP1-52184.

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Buffer
0.5 mg/ml Tris (pH 7.3) and 0.5% BSA
Preservative
0.02% Sodium Azide
Concentration
0.5 mg/ml
Purity
Immunogen affinity purified

Notes

Please note, this antibody is considered Innovators Grade. Innovators Grade antibodies are generally unvalidated and require additional characterization for most new species/applications. Novus has made these antibodies available through our Innovators Reward program. Complete an online review with image, detailing your positive or negative results. In return, you receive a discount voucher for 100% of the purchase price of the reviewed product. Please contact us at innovators@novusbio.com for more details.

Alternate Names for BIRC6 Antibody

  • APOLLON
  • baculoviral IAP repeat containing 6
  • baculoviral IAP repeat-containing 6
  • baculoviral IAP repeat-containing protein 6
  • BRUCE
  • FLJ13786
  • KIAA1289FLJ13726
  • Ubiquitin-conjugating BIR domain enzyme apollon
  • ubiquitin-conjugating BIR-domain enzyme apollon

Background

This gene encodes a protein with a BIR (baculoviral inhibition of apoptosis protein repeat) domain and a UBCc (ubiquitin-conjugating enzyme E2, catalytic) domain. This protein inhibits apoptosis by facilitating the degradation of apoptotic proteins by ubiquitination.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for BIRC6 Antibody (NBP1-52184)(1)

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Product General Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

Video Protocols

ICC/IF Video Protocol

FAQs for BIRC6 Antibody (NBP1-52184) (0)

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics Tool for BIRC6 Antibody (NBP1-52184)

Discover related pathways, diseases and genes to BIRC6 Antibody (NBP1-52184). Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
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Blogs on BIRC6.

cIAP1 - An apoptotic regulator with implications in drug resistant cancers
Cellular inhibitor of apoptosis protein-1 (cIAP-1) is an anti-apoptotic protein that is able to bind to caspases and inhibit their activity. Additionally cIAP-1 contains a RING domain with E3 ubiquitin ligase activity that is able to mediate the r...  Read full blog post.

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Calculators

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Bioinformatics

Gene Symbol BIRC6
Entrez
Uniprot