B4GALNT1 Antibody (1024912) [Alexa Fluor® 647]

• Reactivity: Hu
• Applications: IHC
• Clone: 1024912
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Alexa Fluor 647

B4GALNT1 Antibody (1024912) [Alexa Fluor® 647] Summary

• Immunogen: S. frugiperda insect ovarian cell line Sf 21-derived recombinant human GM2/GD2 Synthase/ B4GALNT1
  Ser26-Gln533
  Accession # Q00973
• Specificity: Detects human GM2/GD2 Synthase/ B4GALNT1 in direct ELISAs.
• Isotype: IgG2b
• Clonality: Monoclonal
• Host: Mouse
• Purity Statement: Protein A or G purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
• Buffer: Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for B4GALNT1 Antibody (1024912) [Alexa Fluor® 647]

• (N-acetylneuraminyl)-galactosylglucosylceramide
• B4GALNT1
• beta-1,4 N-acetylgalactosaminyltransferase 1
• beta1,4GalNAc-T
• beta-1,4-N-acetyl-galactosaminyl transferase 1
• beta1-4GalNAc-T
• GALGT
• GALGTEC 2.4.1.92
• GALNACT
• GalNAc-T
• GD2 Synthase
• GD2 synthase, GM2 synthase
• GM2 Synthase
• GM2/GD2 synthase
• SIAT2
• SPG26
• UDP-Gal:betaGlcNAc beta-1,4-N-acetylgalactosaminyltransferase transferase 1
• UDP-N-acetyl-alpha-D-galactosamine:(N-acetylneuraminyl)-galactosylglucosylceramideN-acetylgalactosaminyltransferase (GalNAc-T)

Background

B4GALNT1, also known as GM2/GD2 Synthase, is an enzyme involved in the biosynthesis of brain-enriched complex gangliosides GM2, GD2, GT2 and GA2 from GM3, GD3, GT3 and GA3.  This is a critical step in the synthesis of all complex gangliosides enriched in the nervous system of vertebrates.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.