ATRX Antibody (60.1)

Immunohistochemistry-Paraffin: ATRX Antibody (60.1) [NBP1-02823] - Staining of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.

Product Discontinued

ATRX Antibody (60.1) Summary

• Immunogen: Combination of N & C peptide, corresponding to a range between amino acids 1-300 and 450-741
• Specificity: Peptides from N and C termini of ATRX
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Gene: ATRX
• Purity: Protein G purified

Applications/Dilutions

• Dilutions:
  • ELISA 1:100-1:2000
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Paraffin 5 ug/ml
  • Western Blot 1:100-1:2000

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.2)
• Preservative: No Preservative
• Concentration: 1 mg/ml
• Purity: Protein G purified

Alternate Names for ATRX Antibody (60.1)

• alpha thalassemia/mental retardation syndrome X-linked (RAD54 (S. cerevisiae)homolog)
• alpha thalassemia/mental retardation syndrome X-linked (RAD54 homolog, S.cerevisiae)
• alpha thalassemia/mental retardation syndrome X-linked
• ATP-dependent helicase ATRX
• ATR2
• DNA dependent ATPase and helicase
• EC 3.6.1
• EC 3.6.4.12
• helicase 2, X-linked
• Juberg-Marsidi syndrome
• MGC2094
• MRXHF1
• RAD54 homolog
• RAD54L
• SFM1
• SHS
• transcriptional regulator ATRX
• XH2RAD54
• X-linked helicase II
• X-linked nuclear protein
• XNPZNF-HX
• Zinc finger helicase
• Znf-HX

Background

The protein encoded by this gene belongs to the DEAD-like helicase superfamily, and shares similarity with Saccharomyces cerevisiae Rad54, a protein known to be involved in the homologous recombination and repair of DNA. This protein has been shown to play a role in homologous recombination related repair of DNA double-strand breaks. The binding of this protein to double-strand DNA induces a DNA topological change, which is thought to facilitate homologous DNA paring, and stimulate DNA recombination.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: ATRX
• Entrez:
  • 546(Human)
• Uniprot:
  • P46100(Human)