ATP6V0C Antibody [Janelia Fluor® 585]

Product Discontinued

ATP6V0C Antibody [Janelia Fluor® 585] Summary

• Immunogen: Produced in rabbits immunized with a synthetic peptide corresponding to the center region of the Human ATP6V0C.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: ATP6V0C
• Purity: Antigen and protein A Affinity-purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry-Paraffin
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Antigen and protein A Affinity-purified

Notes

Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for ATP6V0C Antibody [Janelia Fluor® 585]

• ATP6CATPase, H+ transporting, lysosomal (vacuolar proton pump) 16kD
• ATP6LVPPC
• ATPase, H+ transporting, lysosomal 16kDa, V0 subunit c
• ATPL
• H(+)-transporting two-sector ATPase, 16 kDa subunit
• vacuolar ATP synthase 16 kDa proteolipid subunit
• vacuolar H+ ATPase proton channel subunit
• Vacuolar proton pump 16 kDa proteolipid subunit
• VATL
• V-ATPase 16 kDa proteolipid subunit
• Vma3
• V-type proton ATPase 16 kDa proteolipid subunit

Background

ATP6V0C encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c', c", and d. Additional isoforms of many of the V1 and V0 subunit proteins are encoded by multiple genes or alternatively spliced transcript variants. This encoded protein is part of the V0 domain. This gene had the previous symbols of ATP6C and ATP6L. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: ATP6V0C