ATP11B Antibody

Images

 
Western Blot: ATP11B Antibody [NBP1-77190] - K562 cell tissue lysate with ATP11B antibody at 1 ug/mL in (A) the absence and (B) the presence of blocking peptide.
Immunocytochemistry/ Immunofluorescence: ATP11B Antibody [NBP1-77190] - K562 cells with ATP11B antibody at 10 ug/mL.
Immunofluorescence: ATP11B Antibody [NBP1-77190] - K562 cells 20 ug/mL.

Product Details

Summary
Reactivity Hu, MuSpecies Glossary
Applications WB, ELISA, ICC/IF, ICC/IF
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
1 mg/ml

Order Details

ATP11B Antibody Summary

Immunogen
Antibody was raised against a 19 amino acid synthetic peptide near the amino terminus of human ATP11B. The immunogen is located within amino acids 290 - 340 of ATP11B.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
ATP11B
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Western Blot 1:100-1:2000
  • ELISA 1:100-1:2000
  • Immunocytochemistry/Immunofluorescence 1:10-1:2000
  • Immunofluorescence 20 ug/mL.
Control Peptide
ATP11B Peptide (NBP1-77190PEP)

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS
Preservative
0.02% Sodium Azide
Concentration
1 mg/ml
Purity
Immunogen affinity purified

Alternate Names for ATP11B Antibody

  • ATPase class VI type 11B
  • ATPase IR
  • ATPase, class VI, type 11B
  • ATPIFKIAA0956probable phospholipid-transporting ATPase IF
  • ATPIRMGC46576
  • DKFZp434J238
  • DKFZp434N1615
  • EC 3.6.3
  • EC 3.6.3.1

Background

ATP11B is a widely expressed integral membrane ATPase and is thought to drive the transport of phospholipids across membranes. It has been suggested that ATP11B is hormonally regulated and plays a role in the subnuclear trafficking of transcription factors with RING motifs. While the exact molecule ATP11B transports is unknown, increased mRNA expression of the homologous ATP11A has been observed in cells resistant to anti-cancer drugs such as farnesyltransferase inhibitors (FTIs), suggesting that ATP11B may also play a role in cell survival under harsh conditions.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol
ICC/IF Video Protocol

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol ATP11B
Uniprot