ATP11A Antibody - BSA Free

Western Blot: ATP11A Antibody [NBP1-77189] - K562 cell tissue lysate with ATP11A antibody at 1 ug/mL in (A) the absence and (B) the presence of blocking peptide.

Immunocytochemistry/ Immunofluorescence: ATP11A Antibody - BSA Free [NBP1-77189] - Immunocytochemistry of ATP11A in K562 cells with ATP11A antibody at 10 u/mL.

Immunocytochemistry/ Immunofluorescence: ATP11A Antibody - BSA Free [NBP1-77189] - Immunofluorescence of ATP11A in K562 cells with ATP11A antibody at 20 ug/mL.

• Reactivity: Hu, Mu, Rt
• Applications: WB, ELISA, ICC/IF
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free
• Concentration: 1 mg/ml

ATP11A Antibody - BSA Free Summary

• Description: Novus Biologicals Rabbit ATP11A Antibody - BSA Free (NBP1-77189) is a polyclonal antibody validated for use in WB, ELISA and ICC/IF. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: Antibody was raised against a 19 amino acid synthetic peptide near the amino terminus of human ATP11A. The immunogen is located within the first 50 amino acids of ATP11A. Amino Acid Squence: CREPPPGAEAYIPQRYPDNR
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: ATP11A
• Purity: Peptide affinity purified

Applications/Dilutions

• Dilutions:
  • ELISA 1:100-1:2000
  • Immunocytochemistry/ Immunofluorescence 10-20 ug/ml
  • Western Blot 1 ug/ml
• Control Peptide:

  ATP11A Peptide (NBP1-77189PEP)

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS
• Preservative: 0.02% Sodium Azide
• Concentration: 1 mg/ml
• Purity: Peptide affinity purified

Alternate Names for ATP11A Antibody - BSA Free

• ATPase, class VI, type 11A

Background

ATP11A is a widely expressed integral membrane ATPase. ATP11A is probably phosphorylated in its intermediate state and likely drives the transport of ions such as calcium or other molecules across membranes. While the exact molecule ATP11A transports is unknown, increased expression of ATP11A mRNA has been observed in murine leukemia cells made resistant to anti-cancer drugs such as farnesyltransferase inhibitors (FTIs). Furthermore, overexpression of ATP11A provided protection against the FTI SCH66336 while knockdown of ATP11A via siRNA made cells more sensitive to this drug. Other reports suggest that elevated levels of ATP11A mRNA may also be a predictive marker of metastasis in colorectal cancer patients.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: ATP11A
• Uniprot:
  • NP_115565(Human)