ASAH3 Antibody Summary
Synthetic peptides corresponding to the C terminal of ACER1.
Immunizing peptide sequence VNAYALNSIALHILYIVCQEYRKTSNKELRHLIEVSVVLWAVALTSWISD.
Immunogen affinity purified
Test in a species/application not listed above to receive a full credit towards a future purchase.
Packaging, Storage & Formulations
Store at -20C. Avoid freeze-thaw cycles.
PBS & 2% Sucrose.
Please see the vial label for concentration. If unlisted please contact technical services.
Immunogen affinity purified
This is a rabbit polyclonal antibody against ACER1 and was validated on Western blot.
The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
The addition of 50% glycerol is optional for those storing this antibody at -20C and not aliquoting smaller units. However, please note that glycerol may interrupt some downstream antibody applications and should be added with caution.
Alternate Names for ASAH3 Antibody
- Acylsphingosine deacylase 3
- Alkaline CDase 1
- alkaline ceramidase 1
- AlkCDase 1
- EC 184.108.40.206
- N-acylsphingosine amidohydrolase (alkaline ceramidase) 3
- N-acylsphingosine amidohydrolase 3
ACER1 hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid at an optimal pH of 8.0. It has a highly restricted substrate specificity for the natural stereoisomer of ceramide with D-erythro-sphingosine but not D-ribo-phytosphingosine or D-erythro-dihydrosphingosine as a backbone. It may have a role in regulating the levels of bioactive lipids ceramide and sphingosine 1-phosphate, as well as complex sphingolipids.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed
for 1 year from date of receipt.
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