ARPC1A Antibody (RB17836)

Product Discontinued

ARPC1A Antibody (RB17836) Summary

• Immunogen: This ARPC1A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 286-315 amino acids from the C-terminal region of human ARPC1A.
• Localization: Cellular Location Cytoplasm, cytoskeleton (Probable).
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: ARPC1A
• Purity: Ammonium sulfate precipitation

Applications/Dilutions

• Dilutions:
  • Flow Cytometry 1:10 - 1:50
  • Immunocytochemistry/ Immunofluorescence 1:10 - 1:50
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin 1:10 - 1:50
  • Western Blot 1:1000
• Theoretical MW: 41.569 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Reactivity Notes

Predicted to react with Bovine, Mouse and Rat.

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS
• Preservative: 0.09% Sodium Azide
• Concentration: 3.97 mg/ml
• Purity: Ammonium sulfate precipitation

Alternate Names for ARPC1A Antibody (RB17836)

• actin binding protein (Schizosaccharomyces pombe sop2-like)
• actin related protein 2/3 complex, subunit 1A (41 kD)
• actin related protein 2/3 complex, subunit 1A, 41kDa
• actin-related protein 2/3 complex subunit 1A
• SOP2Hs
• SOP2LArc40
• SOP2-like protein

Background

ARPC1A is one of seven subunits of the human Arp2/3 protein complex. This subunit is a member of the SOP2 family of proteins and is most similar to the protein ARPC1B. The similarity between these two proteins suggests that they both may function as p41 subunit of the human Arp2/3 complex that has been implicated in the control of actin polymerization in cells. It is possible that the p41 subunit is involved in assembling and maintaining the structure of the Arp2/3 complex. Multiple versions of the p41 subunit may adapt the functions of the complex to different cell types or developmental stages.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: ARPC1A
• Uniprot:
  • Q92747(Human)