ARFGEF2 Antibody (24GB6840)

• Reactivity: Hu, Mu, Rt
• Applications: WB
• Clone: 24GB6840
• Clonality: Monoclonal
• Host: Rabbit
• Conjugate: Unconjugated

ARFGEF2 Antibody (24GB6840) Summary

• Immunogen: A synthesized peptide derived from human ARFGEF2 (Uniprot: Q9Y6D5)
• Isotype: IgG
• Clonality: Monoclonal
• Host: Rabbit
• Gene: ARFGEF2
• Purity: Affinity purified

Applications/Dilutions

• Dilutions:
  • Western Blot

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.4), 50% glycerol
• Preservative: 0.02% Sodium Azide
• Purity: Affinity purified

Alternate Names for ARFGEF2 Antibody (24GB6840)

• ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldinA-inhibited)
• ARFGEP2
• BIG2brefeldin A-inhibited guanine nucleotide-exchange protein 2
• Brefeldin A-inhibited GEP 2
• dJ1164I10.1
• FLJ23723
• PVNH2

Background

BIG2 promotes guanine-nucleotide exchange on ARF1, ARF5 and ARF6. Promotes the activation of ARF1/ARF5/ARF6 through replacement of GDP with GTP. [from: http://www.genecards.org/cgi-bin/carddisp.pl®gene=ARFGEF2&search=BIG2] ARFGEF2 plays an important role in vesicular and membrane trafficking from the trans-golgi network. It is also involved in the activation of ARFs (1,5, and 6) by accelerating replacement of bound GDP with GTP. It also acts as the activator of ADP-ribosylation factor GTPases that are essential for regulating vesicular traffic among intracellular organelles. [from: http://www.dsi.univ-paris5.fr/genatlas/fiche.php®symbol=ARFGEF2]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: ARFGEF2