ARFGEF2 Products

Antibodies
ARFGEF2 Antibody
ARFGEF2 Antibody
NBP1-88607
Species: Hu
Applications: WB, ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
ARFGEF2 Antibody
ARFGEF2 Antibody
35480002
Species: Hu
Applications: ELISA, IHC, IHC-P
Host: Rabbit Polyclonal
Proteins
ARFGEF2 Recombinant Protein A ...
ARFGEF2 Recombinant Protein Antigen
NBP1-88607PEP
Species: Hu
Applications: AC

Description

BIG2 promotes guanine-nucleotide exchange on ARF1, ARF5 and ARF6. Promotes the activation of ARF1/ARF5/ARF6 through replacement of GDP with GTP. [from: http://www.genecards.org/cgi-bin/carddisp.pl®gene=ARFGEF2&search=BIG2] ARFGEF2 plays an important role in vesicular and membrane trafficking from the trans-golgi network. It is also involved in the activation of ARFs (1,5, and 6) by accelerating replacement of bound GDP with GTP. It also acts as the activator of ADP-ribosylation factor GTPases that are essential for regulating vesicular traffic among intracellular organelles. [from: http://www.dsi.univ-paris5.fr/genatlas/fiche.php®symbol=ARFGEF2]

Bioinformatics

Entrez Human
Rat
Uniprot Human
Product By Gene ID 10564
Alternate Names
  • ARFGEP2
  • PVNH2
  • dJ1164I10.1
  • Brefeldin A-inhibited GEP 2
  • BIG2brefeldin A-inhibited guanine nucleotide-exchange protein 2
  • FLJ23723
  • ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldinA-inhibited)

PTMs for ARFGEF2

Learn more about PTMs related to ARFGEF2.

Ribosylation
Phosphorylation
Cleavage

Bioinformatics Tool for ARFGEF2

Discover related pathways, diseases and genes to ARFGEF2. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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