Aquaporin-4 Antibody (1093722) [Alexa Fluor® 750]

• Reactivity: Hu
• Applications: IHC
• Clone: 1093722
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Alexa Fluor 750

Aquaporin-4 Antibody (1093722) [Alexa Fluor® 750] Summary

• Immunogen: Synthetic Peptide
  Accession # P55087
• Specificity: Detects a synthetic peptide specific for human Aquaporin-4 around aa 315 in Direct ELISA.
• Isotype: IgG
• Clonality: Monoclonal
• Host: Mouse
• Purity Statement: Protein A or G purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
• Buffer: Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Aquaporin-4 Antibody (1093722) [Alexa Fluor® 750]

• AQP4
• AQP-4
• Aquaporin 4
• MGC22454
• MIWC
• WCH4

Background

Aquaporin 4, AQP4, is a 35kDa water channel protein that plays an important role in brain water homeostasis.  AQP4 is highly expressed in the end feet of astrocytes in the brain and CNS with the largest presence in the cerebellum and spinal cord grey matter.  It can also be located in epithelial cells of many organs throughout the body.  The main function of AQP4 is to provide fast water transportation and homeostatic balance throughout the central nervous system.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.