APXL Antibody

Immunohistochemistry-Paraffin: APXL Antibody [NB100-1350] - Staining of Human Kidney. Steamed antigen retrieval with Tris/EDTA buffer pH 9, HRP-staining.

• Reactivity: Hu, Bv
• Applications: ELISA, IHC
• Clonality: Polyclonal
• Host: Goat
• Conjugate: Unconjugated
• Concentration: 0.5 mg/ml

APXL Antibody Summary

• Description: Novus Biologicals Goat APXL Antibody (NB100-1350) is a polyclonal antibody validated for use in IHC and ELISA. Anti-APXL Antibody: Cited in 1 publication. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: Peptide with sequence KCLLDSLQPERGK corresponding to C-Terminus according to NP_001640.
• Predicted Species: Bovine (100%). Backed by our 100% Guarantee.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Goat
• Gene: SHROOM2
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry 4 - 6 ug/ml
  • Immunohistochemistry-Paraffin 1:10-1:500
  • Peptide ELISA Detection limit 1:32000
• Application Notes: IHC-P: Human kidney shows cytoplasm staining in PCT exclusively.

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA
• Preservative: 0.02% Sodium Azide
• Concentration: 0.5 mg/ml
• Purity: Immunogen affinity purified

Alternate Names for APXL Antibody

• apical protein, Xenopus laevis-like
• apical protein-like (Xenopus laevis)
• Apical-like protein
• APX homolog of Xenopus
• APXLHSAPXL
• DKFZp781J074
• FLJ39277
• Protein APXL
• protein Shroom2
• shroom family member 2

Background

The protein encoded by the APXL gene shares significant similarities with the apical protein from Xenopus laevis which isimplicated in amiloride-sensitive sodium channel activity. This gene is a strong candidate gene for ocular albinismtype 1 syndrome. (provided by RefSeq)

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for APXL Antibody (NB100-1350)(1)

Publication using NB100-1350

• Schiaffino MV, Bassi MT, Rugarli EI et al. Cloning of a human homologue of the Xenopus laevis APX gene from the ocular albinism type 1 critical region. Hum Mol Genet 1995-03-01 [PMID: 7795590]

Bioinformatics

• Gene Symbol: SHROOM2
• Entrez:
  • 357(Human)
• Uniprot:
  • NP_001640.(Human)