APEG1 Antibody

Product Discontinued

APEG1 Antibody Summary

• Immunogen: Peptide with sequence ERIARKPTVCESEIR corresponding to internal region according to NP_005867.3.
• Specificity: This antibody is expected to recognize isoform 1 only (NP_005867.3).
• Isotype: IgG
• Clonality: Polyclonal
• Host: Goat
• Gene: SPEG
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Peptide ELISA Detection limit 1:128000
  • Western Blot 1:100 - 1:2000
• Application Notes: WB: Not yet tested - Our standard WB protocol would not expect to reliably detect proteins as large as the calculated size of 354 kDa band according to NP_005867.3.

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA
• Preservative: 0.02% Sodium Azide
• Concentration: 0.5 mg/ml
• Purity: Immunogen affinity purified

Notes

Please note, this antibody is considered to be "Innovators Grade". Innovators Grade antibodies have been validated for limited uses and require additional characterization for most new species/applications. These antibodies are directed against antigens that have limited or no commercial antibodies available for them, or for which there are limited expression data available to us. In an effort to encourage customer feedback, Novus has made these antibodies available through our Innovators Reward program. Under this program, Novus will provide you a 50% refund on the purchased product as well as a 50% discount on a future product of equal value in exchange for your new data. Please contact us at innovators@novusbio.com for more details.

Alternate Names for APEG1 Antibody

• aortic preferentially expressed gene 1
• Aortic preferentially expressed protein 1
• APEG1
• BPEG
• EC 2.7.11
• EC 2.7.11.1
• KIAA1297APEG-1
• MGC12676
• nuclear protein, marker for differentiated aortic smooth muscle anddown-regulated with vascular injury
• SPEG complex locus
• SPEGalpha
• SPEGbeta
• striated muscle preferentially expressed protein kinase

Background

Expression of this gene is thought to serve as a marker for differentiated vascular smooth muscle cells which may have a role in regulating growth and differentiation of this cell type. The encoded protein is highly similar to the corresponding rat and mouse proteins. Multiple alternatively spliced transcript variants have been found for this gene, but the full-length nature of only one variant has been defined.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for APEG1 Antibody (NBP2-26072)(1)

Publication using NBP2-26072

• Hsieh CM, Yoshizumi M, Endege WO et al. APEG-1, a novel gene preferentially expressed in aortic smooth muscle cells, is down-regulated by vascular injury. J Biol Chem 1996-07-19 [PMID: 8663449]

Bioinformatics

• Gene Symbol: SPEG
• Entrez:
  • 10290(Human)