APBA1 Antibody [Alexa Fluor® 488]

• Reactivity: Hu, Mu, Rt
• Applications: WB, ELISA
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Alexa Fluor 488

APBA1 Antibody [Alexa Fluor® 488] Summary

• Immunogen: Antibody was raised against a 12 amino acid synthetic peptide near the center of the mouse UROP11. The immunogen is located within the first 50 amino acids of UROP11. Amino Acid Squence: FHLPRYRNKAKS
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: APBA1
• Purity: Peptide affinity purified

Applications/Dilutions

• Dilutions:
  • ELISA
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Reactivity Notes

0

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Peptide affinity purified

Notes

Alexa Fluor (R) products are provided under an intellectual property license from Life Technologies Corporation. The purchase of this product conveys to the buyer the non-transferable right to use the purchased product and components of the product only in research conducted by the buyer (whether the buyer is an academic or for-profit entity). The sale of this product is expressly conditioned on the buyer not using the product or its components, or any materials made using the product or its components, in any activity to generate revenue, which may include, but is not limited to use of the product or its components: (i) in manufacturing; (ii) to provide a service, information, or data in return for payment; (iii) for therapeutic, diagnostic or prophylactic purposes; or (iv) for resale, regardless of whether they are resold for use in research. For information on purchasing a license to this product for purposes other than as described above, contact Life Technologies Corporation, 5791 Van Allen Way, Carlsbad, CA 92008 USA or outlicensing@lifetech.com. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for APBA1 Antibody [Alexa Fluor® 488]

• Adapter protein X11alpha
• amyloid beta (A4) precursor protein-binding, family A, member 1
• amyloid beta A4 precursor protein-binding family A member 1
• D9S411Eadaptor protein X11alpha
• LIN10
• mint-1
• MINT1amyloid beta (A4) precursor protein-binding, family A, member 1 (X11)
• Neuronal Munc18-1-interacting protein 1
• Neuron-specific X11 protein
• phosphotyrosine-binding/-interacting domain (PTB)-bearing protein
• UROP11
• X11A
• X11X11ALPHA

Background

APBA1 is encoded by this gene is a member of the X11 protein family. It is a neuronal adapter protein that interacts with the Alzheimer's disease amyloid precursor protein (APP). It stabilizes APP and inhibits production of proteolytic APP fragments including the A beta peptide that is deposited in the brains of Alzheimer's disease patients. This gene product is believed to be involved in signal transduction processes. It is also regarded as a putative vesicular trafficking protein in the brain that can form a complex with the potential to couple synaptic vesicle exocytosis to neuronal cell adhesion. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: APBA1