AP-2 beta/TFAP2B Antibody (AP2b beta 1G6/2)

Product Discontinued

AP-2 beta/TFAP2B Antibody (AP2b beta 1G6/2) Summary

• Immunogen: Truncated AP-2 beta protein prepared from bacteria
• Localization: Nuclear
• Isotype: IgG2b
• Clonality: Monoclonal
• Host: Mouse
• Gene: TFAP2B
• Purity: Protein A or G purified

Applications/Dilutions

• Dilutions:
  • ELISA 1:100 - 1:2000
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin 1:10 - 1:500
  • Immunoprecipitation 1:10 - 1:500
  • Western Blot 1:100 - 1:2000
• Application Notes: Positive control(s): Human breast cancer line MDA MB 453.
• Theoretical MW: 50 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
• Control:

  Beta 2 Adaptin Overexpression Lysate

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS
• Preservative: 0.02% Sodium Azide
• Concentration: 1 mg/ml
• Purity: Protein A or G purified

Alternate Names for AP-2 beta/TFAP2B Antibody (AP2b beta 1G6/2)

• activating enhancer binding protein 2 beta
• Activating enhancer-binding protein 2-beta
• AP2 beta
• AP-2 beta
• AP-2B
• AP2-B
• AP2-beta
• CHAR
• MGC21381
• TFAP2B
• transcription factor AP-2 beta (activating enhancer binding protein 2 beta)
• transcription factor AP-2 beta (activating enhancer-binding protein 2 beta)
• transcription factor AP-2-beta

Background

Sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes. AP2 factors bind to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in a large spectrum of important biological functions including proper eye, face, body wall, limbs and neural tube development. They also suppress a number of genes including MCAM/MUC18, C/EBP alpha and MYC. AP2 beta appears to be required for normal face and limb development and for proper terminal differentiation and function of renal tubular epithelia.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: TFAP2B
• Entrez:
  • 7021(Human)