Recombinant Human Annexin A2 Protein

Product Discontinued

Recombinant Human Annexin A2 Protein Summary

• Description: Purified recombinant human 6x His-tagged annexin II.
  
  

  Source:E.coli

  Amino Acid Sequence:UniProt P07355

• Preparation Method: Purified recombinant 6xHis-tagged ANXA2 expressed in E.coli
• Source: E. coli
• Protein/Peptide Type: Recombinant Protein
• Gene: ANXA2
• Endotoxin Note: Less than 0.1 ng/ug

Applications/Dilutions

• Dilutions:
  • ELISA
  • Western Blot
• Theoretical MW: 39.5 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

• Storage: Store at -80C. Avoid freeze-thaw cycles.
• Buffer: PBS
• Concentration: 0.1 mg/ml

Alternate Names for Recombinant Human Annexin A2 Protein

• Annexin A2
• Annexin II
• annexin-2
• ANX2
• ANX2L4
• ANX2L4LPC2
• ANXA2
• CAL1H
• Calpactin I heavy chain
• calpactin I heavy polypeptide
• Calpactin-1 heavy chain
• chromobindin 8
• chromobindin-8
• LIP2
• LIP2PAP-IV
• Lipocortin II
• Lipocortin-2
• LPC2D
• LPC2DP36
• p36
• PAP-IV
• Placental anticoagulant protein IV
• Protein I

Background

The Annexins are a family of structurally similar proteins. Annexins bind to phospholipids and may be involved in regulation of membrane transport, membrane channel activity, and interaction of the cell membrane with the extracellular matrix. Annexin II is a calcium regulated, membrane binding protein whose affinity for calcium is greatly enhanced by anionic phospholipids. It binds two calcium ions with high affinity. This protein functions as an autocrine factor which heightens osteoclast formation and bone resorption. This gene has three pseudogenes located on chromosomes 4, 9 and 10, respectively. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

Bioinformatics

• Gene Symbol: ANXA2