ANKH Antibody (RB24439)

Product Discontinued

ANKH Antibody (RB24439) Summary

• Immunogen: This ANKH antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 464-492 amino acids from the C-terminal region of human ANKH.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: ANKH
• Purity: Protein A purified

Applications/Dilutions

• Dilutions:
  • Flow Cytometry 1:10 - 1:50
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin 1:10 - 1:50
  • Western Blot 1:1000
• Theoretical MW: 54.241 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Reactivity Notes

Predicted to react with Rat.

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS
• Preservative: 0.09% Sodium Azide
• Concentration: 0.45 mg/ml
• Purity: Protein A purified

Alternate Names for ANKH Antibody (RB24439)

• ANKcraniometaphyseal dysplasia, Jackson type (dominant)
• ankylosis, progressive (mouse) homolog
• ankylosis, progressive homolog (mouse)
• CCAL2
• CMDJ
• CPPDDFLJ27166
• HANKMANK
• KIAA1581
• progressive ankylosis protein homolog

Background

ANKH is a multipass transmembrane protein that is expressed in joints and other tissues and controls pyrophosphate levels in cultured cells. Progressive ankylosis-mediated control of pyrophosphate levels has been suggested as a possible mechanism regulating tissue calcification and susceptibility to arthritis in higher animals.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for ANKH Antibody (NBP2-29950)(1)

Publication using NBP2-29950

• Chang CC, Lee KL, Chan TS et al. Histone Deacetylase Inhibitors Downregulate Calcium Pyrophosphate Crystal Formation in Human Articular Chondrocytes International journal of molecular sciences 2022-02-26 [PMID: 35269745] (WB, Human)

Bioinformatics

• Gene Symbol: ANKH
• Uniprot:
  • Q9HCJ1(Human)