Aminopeptidase O/ONPEP Antibody - Azide and BSA Free

Western Blot: Aminopeptidase O/ONPEP Antibody [H00084909-B01P] - Analysis of C9orf3 expression in transfected 293T cell line by C9orf3 polyclonal antibody. Lane 1: C9orf3 transfected lysate(79.2 KDa). Lane 2: Non-transfected lysate.

• Reactivity: Hu
• Applications: WB, ELISA
• Clonality: Polyclonal
• Host: Mouse
• Conjugate: Unconjugated
• Format: Azide and BSA Free

Aminopeptidase O/ONPEP Antibody - Azide and BSA Free Summary

• Immunogen: C9orf3 (NP_116212, 1 a.a. - 720 a.a.) full-length human protein. MDIQLDPARDDLPLMANTSHILVKHYVLDLDVDFESQVIEGTIVLFLEDGNRFKKQNSSIEEACQSESNKACKFGMPEPCHIPVTNARTFSSEMEYNDFAICSKGEKDTSDKDGNHDNQEHASGISSSKYCCDTGNHGSEDFLLVLDCCDLSVLKVEEVDVAAVPGLEKFTRSPELTVVSEEFRNQIVRELVTLPANRWREQLDYYARCSQAPGCGELLFDTDTWSLQIRKTGAQTATDFPHAIRIWYKTKPEGRSVTWTSDQSGRPCVYTVGSPINNRALFPCQEPPVAMSTWQATVRAAASFVVLMSGENSAKPTQLWEECSSWYYYVTMPMPASTFTIAVGCWTEMKMETWSSNDLATERPFSPSEANFRHVGVCSHMEYPCRFQNASATTQEIIPHRVFAPVCLTGACQETLLRLIPPCLSAAHSVLGAHPFSRLDVLIVPANFPSLGMARPSKDKTGHTSDSGASVIKHGLNPEKIFMQVHYLKGYFLLRFLAKRLGDETYFSFLRKFVHTFHGQLILSQDFLQMLLENIPEEKRLELSVENIYQDWLESSGIPKPLQRERRAGAECGLARQVRAEVTKWIGVNRRPRKRKRREKEEVFEKLLPDQLVLLLEHLLEQKTLSPRTLQSLQRTYHLQDQDAEVRHRWCELIVKHKFTKAYKSVERFLQEDQAMGVYLYGELMVSEDARQQQLARRCFERTKEQMDRSSAQVVAEMLF
• Specificity: C9orf3 - chromosome 9 open reading frame 3,
• Isotype: IgG
• Clonality: Polyclonal
• Host: Mouse
• Gene: C9ORF3
• Purity: Protein A purified

Applications/Dilutions

• Dilutions:
  • ELISA
  • Western Blot 1:500
• Application Notes: Antibody reactive against Recombinant Protein with GST tag on ELISA and Western Blot and also on transfected lysate in western blot. GST tag alone is used as a negative control.

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.4)
• Preservative: No Preservative
• Purity: Protein A purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for Aminopeptidase O/ONPEP Antibody - Azide and BSA Free

• Aminopeptidase O
• AOPEP
• APO
• AP-OFLJ55832
• C90RF3
• C9orf3
• chromosome 9 open reading frame 3
• EC 3.4.11.-
• FLJ14675
• FLJ40923
• ONPEP

Background

Aminopeptidases catalyze the hydrolysis of amino acid residues from the N-terminus of peptide or proteinsubstrates. Able to cleave angiotensin III to generate angiotensin IV, a bioactive peptide of the renin-angiotensinpathway. Not able to cleave angiotensin I and angiotensin II. May play a role in the proteolytic processing ofbioactive peptides in tissues such as testis and heart

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for Aminopeptidase O/ONPEP Antibody (H00084909-B01P)(1)

Publication using H00084909-B01P

• Kovacevic L, Lu H, Caruso JA et al. Marked increase in urinary excretion of apolipoproteins in children with nephrolithiasis associated with hypercalciuria. Pediatr. Nephrol. 2017-02-10 [PMID: 28188435] (ELISA, Human)

Bioinformatics

• Gene Symbol: C9ORF3
• Entrez:
  • 84909(Human)
• Uniprot:
  • NP_116212(Human)