AMIGO2 Antibody [Unconjugated]

• Reactivity: Hu
• Applications: WB
• Clonality: Polyclonal
• Host: Goat
• Conjugate: Unconjugated
• Concentration: LYOPH

AMIGO2 Antibody [Unconjugated] Summary

• Immunogen: Mouse myeloma cell line NS0-derived recombinant human AMIGO2
  Gly39-Ala392
  Accession # Q86SJ2
• Specificity: Detects human AMIGO2 in direct ELISAs and Western blots. In direct ELISAs, less than 5% cross-reactivity with recombinant human AMIGO and rhAMIGO3 is observed.
• Source: N/A
• Isotype: IgG
• Clonality: Polyclonal
• Host: Goat
• Gene: AMIGO2
• Purity Statement: Antigen Affinity-purified

Applications/Dilutions

• Dilutions:
  • Western Blot 0.1 ug/mL

Packaging, Storage & Formulations

• Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.
• Buffer: Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
• Preservative: No Preservative
• Concentration: LYOPH
• Reconstitution Instructions: Reconstitute at 0.2 mg/mL in sterile PBS.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for AMIGO2 Antibody [Unconjugated]

• adhesion molecule with Ig-like domain 2
• ALI1amphoterin induced gene 2
• alivin 1
• Alivin-1
• AMIGO2
• AMIGO-2
• DEGAamphoterin-induced protein 2
• differentially expressed in gastric adenocarcinoma
• Differentially expressed in gastric adenocarcinomas
• transmembrane protein AMIGO2

Background

AMIGO2 is a member of the AMIGO family of type I transmembrane proteins that contain 6 leucine-rich repeats (LRRs) and one Ig domain in the extracellular region. AMIGO2 is expressed primarily in cerebellum, retina, liver and lung. AMIGO family proteins are cell adhesion molecules that exhibit homophilic and heterophilic binding properties.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for AMIGO2 Antibody (AF2080)(1)

Publication using AF2080

• Fontanals-Cirera B, Hasson D, Vardabasso C et al. Harnessing BET Inhibitor Sensitivity Reveals AMIGO2 as a Melanoma Survival Gene. Mol Cell 11/16/2017 [PMID: 29149598]

Bioinformatics

• Gene Symbol: AMIGO2
• Uniprot:
  • Q86SJ2()