AMIGO Antibody [Unconjugated]

• Reactivity: Hu
• Applications: WB
• Clonality: Polyclonal
• Host: Sheep
• Conjugate: Unconjugated
• Concentration: LYOPH

AMIGO Antibody [Unconjugated] Summary

• Immunogen: Mouse myeloma cell line NS0-derived recombinant human AMIGO
  Met1-Gly365
  Accession # Q86WK6
• Specificity: Detects human AMIGO in direct ELISAs and Western blots. In direct ELISAs, approximately 5% cross-reactivity with recombinant human (rh) AMIGO2 is observed and less than 1% cross-reactivity with rhAMIGO3 is observed.
• Source: N/A
• Isotype: IgG
• Clonality: Polyclonal
• Host: Sheep
• Gene: AMIGO1
• Purity Statement: Antigen Affinity-purified

Applications/Dilutions

• Dilutions:
  • Western Blot 0.1 ug/mL

Packaging, Storage & Formulations

• Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.
• Buffer: Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
• Preservative: No Preservative
• Concentration: LYOPH
• Reconstitution Instructions: Reconstitute at 0.2 mg/mL in sterile PBS.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for AMIGO Antibody [Unconjugated]

• adhesion molecule with Ig-like domain 1
• ali2
• Alivin-2
• AMIGO
• AMIGO1
• AMIGO-1
• AMIGOamphoterin-induced protein 1
• amphoterin-induced gene and ORF
• KIAA1163

Background

AMIGO is a 65 kDa type I transmembrane glycoprotein that belongs to both the Ig- and LLR (leucine-rich repeat)- superfamilies. It is expressed on developing neuronal fiber tracts and participates in their formation. AMIGO forms both homophilic and heterophilic complexes with AMIGO2 and 3, suggesting an adhesive function for the molecule. Human AMIGO extracellular domain is 87% amino acid identical to mouse AMIGO, and 40% identical to human AMIGO2 and 3.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: AMIGO1
• Uniprot:
  • Q86WK6()