alpha-Fetoprotein/AFP Antibody (189506) [Alexa Fluor™ Plus 680]

• Reactivity: Hu
• Clone: 189506
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Alexa Fluor Plus 680

alpha-Fetoprotein/AFP Antibody (189506) [Alexa Fluor™ Plus 680] Summary

• Specificity: Detects human alpha -Fetoprotein in direct ELISAs.
• Isotype: IgG2b
• Clonality: Monoclonal
• Host: Mouse

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
• Buffer: Supplied 0.2 mg/mL in a saline solution containing BSA and Sodium Azide.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for alpha-Fetoprotein/AFP Antibody (189506) [Alexa Fluor™ Plus 680]

• AFP
• Alpha-1-fetoprotein
• alpha-fetoglobulin
• alpha-Fetoprotein
• DSCAM2
• FETA
• HP
• HPAFP

Background

AFP ( alpha -Fetoprotein) is a 69-73 kDa member of the ALB/AFP/VDB family of proteins. alpha -Fetoprotein is a major plasma protein in the fetus. Its concentration is normally low in the adult except when produced by certain tumors. It is secreted by fetal liver and serves as a carrier molecule for phytoestrogens, heavy metals (Cu and Ni), estrogen and fatty acids. Mature human AFP is 591 amino acids (aa) in length. It contains three albumin domains (aa 19-210, 211-402 and 403-601), plus 15 intrachain disulfide bonds. Mature human AFP shares approximately 66% aa identity with mouse AFP.

1. Matsumura, M. et al. (2001) Hepatol. Res. 20:84
2. Deutsch, H.F. et al. (2000) Tumor Biol. 21:267

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.