alpha-2B Adrenergic R/ADRA2B Antibody (5G10) - BSA Free

Western Blot: alpha-2B Adrenergic R/ADRA2B Antibody (5G10) [NBP2-66606] - alpha2B adrenergic receptor antibody on MDCK cells transfected to produce alpha2B receptor protein.

• Reactivity: Mu, Rt
• Applications: WB, IHC
• Clone: 5G10
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Unconjugated
• Format: BSA Free

alpha-2B Adrenergic R/ADRA2B Antibody (5G10) - BSA Free Summary

• Description: Novus Biologicals Mouse alpha-2B Adrenergic R/ADRA2B Antibody (5G10) - BSA Free (NBP2-66606) is a monoclonal antibody validated for use in IHC and WB. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: Mouse monoclonal antibody raised to a synthetic peptide corresponding to the third intracellular loop of the rat alpha-2B Adrenergic R/ADRA2B (Uniprot: P19328).
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Gene: ADRA2B
• Purity: Protein A or G purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry
  • Western Blot 5-10 ug/ml
• Application Notes: .

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: PBS
• Preservative: 0.08% Sodium Azide
• Purity: Protein A or G purified

Alternate Names for alpha-2B Adrenergic R/ADRA2B Antibody (5G10) - BSA Free

• a-2B AdrenergicR
• ADRA2B adrenergic, alpha-2B-, receptor
• ADRA2B
• ADRA2L1
• ADRA2L1adrenergic receptor alpha 2B
• ADRA2RL1
• ADRARL1
• adrenergic, alpha-2B-, receptor
• Alpha-2 adrenergic receptor subtype C2
• alpha-2-adrenergic receptor-like 1
• alpha-2B Adrenergic R
• alpha-2B adrenergic receptor
• alpha2B AdrenergicR
• Alpha-2B adrenoceptor
• Alpha-2B adrenoreceptor
• alpha-2B-adrenergic receptor
• ALPHA2BAR
• alpha-2BAR
• G-protein coupled receptor

Background

The rat alpha 2b adrenergic receptor is a G protein coupled receptor which acts through Gi2 and is responsible for Cellular communication and signal transduction. These receptors are linked to pertussis toxin-sensitive G proteins. Agonist binding leads to inhibition of adenylyl cyclase, inhibition of Ca(2+) channels and activation of K(+) channels. Recently, three distinct subtypes of alpha(2)-AR were described, alpha(2A)-AR, alpha(2B)-AR and alpha(2C)-AR. At present, it is unknown which of these alpha(2)-AR subtype(s) may regulate insulin secretion.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: ADRA2B
• Uniprot:
  • P19328(Rat)