alpha-2B Adrenergic R/ADRA2B Antibody (5G10)

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Western Blot: alpha-2B Adrenergic R/ADRA2B Antibody (5G10) [NBP2-66606] - alpha2B adrenergic receptor antibody on MDCK cells transfected to produce alpha2B receptor protein.

Product Details

Summary
Reactivity Mu, RtSpecies Glossary
Applications WB, IHC
Clone
5G10
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated

Order Details

alpha-2B Adrenergic R/ADRA2B Antibody (5G10) Summary

Immunogen
Antibody raised to synthetic peptide internal sequence corresponding to the third intracellular loop of rat alpha 2b adrenergic receptor.
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
ADRA2B
Purity
Protein A or G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1:100-1:2000
  • Immunohistochemistry 1:10 - 1:500

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Buffer
PBS
Preservative
0.08% Sodium Azide
Purity
Protein A or G purified

Alternate Names for alpha-2B Adrenergic R/ADRA2B Antibody (5G10)

  • a-2B AdrenergicR
  • ADRA2B adrenergic, alpha-2B-, receptor
  • ADRA2B
  • ADRA2L1
  • ADRA2L1adrenergic receptor alpha 2B
  • ADRA2RL1
  • ADRARL1
  • adrenergic, alpha-2B-, receptor
  • Alpha-2 adrenergic receptor subtype C2
  • alpha-2-adrenergic receptor-like 1
  • alpha-2B Adrenergic R
  • alpha-2B adrenergic receptor
  • alpha2B AdrenergicR
  • Alpha-2B adrenoceptor
  • Alpha-2B adrenoreceptor
  • alpha-2B-adrenergic receptor
  • ALPHA2BAR
  • alpha-2BAR
  • G-protein coupled receptor

Background

The rat alpha 2b adrenergic receptor is a G protein coupled receptor which acts through Gi2 and is responsible for Cellular communication and signal transduction. These receptors are linked to pertussis toxin-sensitive G proteins. Agonist binding leads to inhibition of adenylyl cyclase, inhibition of Ca(2+) channels and activation of K(+) channels. Recently, three distinct subtypes of alpha(2)-AR were described, alpha(2A)-AR, alpha(2B)-AR and alpha(2C)-AR. At present, it is unknown which of these alpha(2)-AR subtype(s) may regulate insulin secretion.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol ADRA2B
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