Aldo-keto Reductase 1B10/AKR1B10 Recombinant Protein Antigen

• Reactivity: Hu
• Applications: AC

Aldo-keto Reductase 1B10/AKR1B10 Recombinant Protein Antigen Summary

• Description: A recombinant protein antigen with a N-terminal His6-ABP tag corresponding to human Aldo-keto Reductase 1B10/AKR1B10.

  Source: E. coli

  Amino Acid Sequence: FKLSDEEMATILSFNRNWRACNVLQ

  Fusion Tag: N-terminal His6ABP (ABP = Albumin Binding Protein derived from Streptococcal Protein G)

  This product is intended to be used as a blocking antigen for antibody competition assays. Any other use of this antigen is done at the risk of the user. The use of this product for commercial production is strictly prohibited. Please contact technical support if you have any questions.

• Source: E. coli
• Protein/Peptide Type: Recombinant Protein Antigen
• Gene: AKR1B10
• Purity: >80% by SDS-PAGE and Coomassie blue staining

Applications/Dilutions

• Dilutions:
  • Antibody Competition 10 - 100 molar excess
• Application Notes: This recombinant antigen is only intended to be used as a blocking agent to confirm antibody specificity with the corresponding antibody, catalog number NBP2-57972.It is purified by IMAC chromatography, and the expected concentration is greater than 0.5 mg/ml.For current lot information, including availability, please contact our technical support team click nb-technical@bio-techne.com
• Theoretical MW: 21 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: PBS and 1M Urea, pH 7.4.
• Preservative: No Preservative
• Purity: >80% by SDS-PAGE and Coomassie blue staining

Alternate Names for Aldo-keto Reductase 1B10/AKR1B10 Recombinant Protein Antigen

• AKR1B10
• AKR1B11
• AKR1B12
• Aldo-keto Reductase 1B10
• aldo-keto reductase family 1 member B10
• aldo-keto reductase family 1, member B10 (aldose reductase)
• aldo-keto reductase family 1, member B11 (aldose reductase-like)
• AldoketoReductase 1B10
• aldose reductase-like 1
• aldose reductase-like peptide
• Aldose reductase-like
• Aldose reductase-related protein
• ALDRLn
• ARL1
• ARL-1SI reductase
• ARP
• EC 1.1.1
• EC 1.1.1.-
• EC 1.1.1.21
• hARP
• HIS
• HSI
• MGC14103
• Small intestine reductase

Background

AKR1B10 encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. This member can efficiently reduce aliphatic and aromatic aldehydes, and it is less active on hexoses. It is highly expressed in adrenal gland, small intestine, and colon, and may play an important role in liver carcinogenesis.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

Bioinformatics

• Gene Symbol: AKR1B10