AGTR-1 Antibody

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Western Blot: AGTR-1 Antibody [NB100-57073] - Staining of Human Liver (A) + peptide (B), Mouse Liver (C) + peptide (D) lysate (35 ug protein in RIPA buffer). Antibody at 0.2 ug/mL. Detected by chemiluminescence.

Product Details

Summary
Reactivity Hu, MuSpecies Glossary
Applications WB, IHC, PEP-ELISA
Clonality
Polyclonal
Host
Goat
Conjugate
Unconjugated
Concentration
0.5 mg/ml

Order Details

AGTR-1 Antibody Summary

Immunogen
Peptide with sequence C-EIQKNKPRNDDIFK corresponding to internal region according to NP_004826.2, NP_033611.1, NP_114038.1, NP_114438.1.
Specificity
All reported variants represent identical protein (NP_000676.1, NP_004826.2, NP_033611.1, NP_114038.1 and NP_114438.1).
Isotype
IgG
Clonality
Polyclonal
Host
Goat
Gene
AGTR1
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 0.1 - 0.3 ug/mL
  • Immunohistochemistry
  • Peptide ELISA Detection limit 1:32000
Application Notes
WB: Approx 38 kDa band observed in Human and Mouse Liver lysates (calculated MW of 41.1 kDa according to Human NP_000676.1 and 40.9 kDa according to Mouse NP_796296.1) Additional bands of unknown identity were also observed at 45 and 75 kDa and were successfully blocked by incubation with the immunizing peptide. Use in Immunohistochemistry reported in scientific literature (PMID: 23335130).
Theoretical MW
41 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Control
Mouse Liver Whole Tissue Lysate (Adult Whole Normal)
Reviewed Applications
Read 1 Review rated 1
using
NB100-57073 in the following applications:

Publications
Read Publications using
NB100-57073 in the following applications:

  • IHC
    1 publication

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Buffer
Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA
Preservative
0.02% Sodium Azide
Concentration
0.5 mg/ml
Purity
Immunogen affinity purified

Alternate Names for AGTR-1 Antibody

  • AG2S
  • AGTR1
  • AGTR-1
  • AGTR1AAngiotensin II type-1 receptor
  • Angiostensin Receptor
  • angiotensin II receptor, type 1
  • angiotensin receptor 1
  • angiotensin receptor 1B
  • AT1
  • AT1AR
  • AT1AT1AR
  • AT1B
  • AT1BR
  • AT1R
  • AT2R1
  • AT2R1A
  • AT2R1AGTR1B
  • AT2R1BAT1BR
  • HAT1R
  • type-1 angiotensin II receptor
  • type-1B angiotensin II receptor

Background

Angiotensin II is a potent vasopressor hormone and a primary regulator of aldosterone secretion. It is an important effector controlling blood pressure and volume in the cardiovascular system. It acts through at least two types of receptors. This gene encodes the type 1 receptor which is thought to mediate the major cardiovascular effects of angiotensin II. This gene may play role in the generation of reperfusion arrhythmias following restoration of blood flow to ischemic or infarcted myocardium. It was previously thought that a related gene, denoted as AGTR1B, existed; however, it is now believed that there is only one type 1 receptor gene in humans. At least four transcript variants have been described for this gene. Additional variants have been described but their full-length nature has not been determined. The entire coding sequence is contained in the terminal exon and is present in all transcript variants.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for AGTR-1 Antibody (NB100-57073)(2)

We have publications tested in 1 confirmed species: Mouse.

We have publications tested in 1 application: IHC.


Filter By Application
IHC
(1)
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Filter By Species
Mouse
(1)
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Review for AGTR-1 Antibody (NB100-57073) (1) 11

Average Rating: 1
(Based on 1 review)
We have 1 review tested in 1 species: Mouse.

Reviews using NB100-57073:
Filter by Applications
WB
(1)
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Filter by Species
Mouse
(1)
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Images Ratings Applications Species Date Details
  1
reviewed by:
Kristine DeLeon-Pennell
WB Mouse 11/30/2016
View

Summary

ApplicationWestern Blot
Sample Testedcardiac tissue
SpeciesMouse

Product General Protocols

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Video Protocols

WB Video Protocol

FAQs for AGTR-1 Antibody (NB100-57073) (0)

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Control Lysate(s)

Secondary Antibodies

 

Isotype Controls

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Blogs on AGTR-1

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Recent Reviews

1
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1
1

 
Kristine DeLeon-Pennell
11/30/2016
Application: WB
Species: Mouse

Bioinformatics

Gene Symbol AGTR1
Entrez
Uniprot