ADAMTS15 Antibody (561819) [Alexa Fluor® 750]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications Flow
Clone
561819
Clonality
Monoclonal
Host
Mouse
Conjugate
Alexa Fluor 750
Concentration
Please see the vial label for concentration. If unlisted please contact technical services.

ADAMTS15 Antibody (561819) [Alexa Fluor® 750] Summary

Immunogen
Chinese hamster ovary cell line CHO-derived recombinant human ADAMTS15
Gly18-Cys682
Accession # Q8TE58
Specificity
Detects human ADAMTS15 in direct ELISAs and Western blots.
Isotype
IgG2b
Clonality
Monoclonal
Host
Mouse
Gene
ADAMTS15
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Flow Cytometry 0.25-1 ug/10^6 cells
Application Notes
Flow Cytometry: Please use 0.25-1 ug of conjugated antibody per 10e6 cells.

Packaging, Storage & Formulations

Storage
Store the unopened product at 2 - 8 °C. Do not use past expiration date.
Buffer
Supplied 0.2 mg/mL in a saline solution containing BSA and Sodium Azide.
Preservative
0.09% Sodium Azide
Concentration
Please see the vial label for concentration. If unlisted please contact technical services.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for ADAMTS15 Antibody (561819) [Alexa Fluor® 750]

  • A disintegrin and metalloproteinase with thrombospondin motifs 15
  • a disintegrin-like and metalloprotease (reprolysin type) with thrombospondintype 1 motif, 15
  • a disintegrin-like and metalloprotease (reprolysin type) with thrombospondintype 1 motif, 15, preproprotein
  • ADAM metallopeptidase with thrombospondin type 1 motif, 15
  • ADAM-TS 15
  • ADAMTS15
  • ADAM-TS15
  • ADAMTS-15
  • EC 3.4.24
  • EC 3.4.24.-
  • EC 3.4.24.14
  • EC 3.4.24.82
  • metalloprotease disintegrin 15 with thrombospondin domains
  • MGC126403

Background

A disintegrin and metalloproteinase with thrombospondin motifs 15 (ADAMTS15) is a secreted multi-domain protease that is primarily expressed in fetal liver and kidney. ADAMTS1, 4, 5, 8, and 15 form a subfamily of ADAMTS proteases that possess aggrecanase activity. These proteins are synthesized as zymogens which have a pro-domain that is removed by furin-like protein convertases. ADAMTS15 functions as a suppressor of tumor growth and invasion. It is downregulated in colon cancer, and its expression in breast cancer correlates with poor prognosis. Within amino acids (aa) 18-682 (which includes the propeptide, peptidase, disintegrin, first TSP-1 and most of the Cys-rich domain), human ADAMTS15 shares 95% aa sequence identity with mouse and rat ADAMTS15.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Secondary Antibodies

 

Isotype Controls

Other Available Formats

Alexa Fluor 350 FAB5149U
Alexa Fluor 405 FAB5149V
Alexa Fluor 488 FAB5149G
Alexa Fluor 594 FAB5149T
Alexa Fluor 647 FAB5149R
Alexa Fluor 700 FAB5149N
Alexa Fluor 750 FAB5149S

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Contact Information

Learn the difference between western blot and simple western

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Calculators

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Bioinformatics

Gene Symbol ADAMTS15
Uniprot