ADAM15 Antibody (140104)

• Reactivity: Mu
• Applications: WB
• Clone: 140104
• Clonality: Monoclonal
• Host: Rat
• Conjugate: Unconjugated

ADAM15 Antibody (140104) Summary

• Immunogen: S. frugiperda insect ovarian cell line Sf 21-derived recombinant mouse ADAM15
  Arg18-Ser694
  Accession # O88839
• Specificity: Detects mouse ADAM15 Ectodomain in Western blots. In Western blots, no cross-reactivity with recombinant human ADAM8, 9, 15, 17, or recombinant mouse ADAM10 is observed.
• Source: N/A
• Isotype: IgG2a
• Clonality: Monoclonal
• Host: Rat
• Gene: ADAM15
• Purity Statement: Protein A or G purified from hybridoma culture supernatant

Applications/Dilutions

• Dilutions:
  • Western Blot 1 ug/mL

Packaging, Storage & Formulations

• Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.
• Buffer: Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
• Preservative: No Preservative
• Reconstitution Instructions: Reconstitute at 0.5 mg/mL in sterile PBS.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for ADAM15 Antibody (140104)

• ADAM 15
• ADAM metallopeptidase domain 15
• ADAM15
• disintegrin-like, and cysteine-rich protein 15
• EC 3.4.24
• MDC15
• MDC-15
• Metargidin

Background

ADAM15, also known as MDC15 or metargidin, is a widely expressed metalloproteinase. It is a type I membrane protein that may be involved in cell adhesion and shedding of cell surface proteins.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for ADAM15 Antibody (MAB945)(1)

Publication using MAB945

• Xie B, Shen J, Dong A, Swaim M, Hackett SF, Wyder L, Worpenberg S, Barbieri S, Campochiaro PA An Adam15 amplification loop promotes vascular endothelial growth factor-induced ocular neovascularization. FASEB J., 2008-04-01;22(8):2775-83. 2008-04-01 [PMID: 18381816] (Western Blot, Mouse)

Bioinformatics

• Gene Symbol: ADAM15
• Uniprot:
  • O88839()