Activin RIIB Antibody Blocking Peptide

Product Discontinued

Activin RIIB Antibody Blocking Peptide Summary

• Description: A human Activin RIIB antibody blocking peptide.

  Source: Synthetic

  (Accession #: AAH96245)
  
  For longer periods of storage, aliquot and store at -20C. Avoid repeat freeze-thaw cycles.

• Source: Synthetic
• Protein/Peptide Type: Antibody Blocking Peptide
• Gene: ACVR2B
• Purity: N/A

Applications/Dilutions

• Dilutions:
  • Antibody Competition
  • Western Blot
• Application Notes: This peptide is useful as a blocking peptide for NBP1-59708. This synthetic peptide is designed for use in an antibody competition assay with its corresponding antibody. Use of this product in any other assay has not yet been tested.
  
  For further blocking peptide related protocol, click here.

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: Lyophilized with sterile distilled water.
• Preservative: No Preservative
• Concentration: LYOPH
• Purity: N/A
• Reconstitution Instructions: Reconstitute with 100ul of sterile PBS for a final peptide concentration of 1 mg/ml.

Alternate Names for Activin RIIB Antibody Blocking Peptide

• activin A receptor, type IIB
• Activin receptor type IIB
• activin receptor type-2B
• Activin RIIB
• ActivinRIIB
• ACTRIIB
• ACTR-IIB
• ACVR2B
• EC 2.7.11
• EC 2.7.11.30
• MGC116908

Background

Activin receptors are all transmembrane proteins, composed of a ligand-binding extracellular domain with cysteine-rich region, a transmembrane domain, and a cytoplasmic domain with predicted serine/threonine specificity. Type I receptors are essential for signaling; and type II receptors are required for binding ligands and for expression of type I receptors. Type I and II receptors form a stable complex after ligand binding, resulting in phosphorylation of type I receptors by type II receptors. Type II receptors are considered to be constitutively active kinases. ACVR2B is activin A type IIB receptor, which displays a 3- to 4-fold higher affinity for the ligand than activin A type II receptor.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

Bioinformatics

• Gene Symbol: ACVR2B