ACOT8 Antibody (4D10) [Janelia Fluor® 669]

• Reactivity: Hu
• Applications: WB, ELISA, Flow, ICC/IF
• Clone: 4D10
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Janelia Fluor 669

ACOT8 Antibody (4D10) [Janelia Fluor® 669] Summary

• Immunogen: Recombinant human ACOT8 (1-319aa) purified from E. coli
• Isotype: IgG2a Kappa
• Clonality: Monoclonal
• Host: Mouse
• Gene: ACOT8
• Purity: Protein A purified

Applications/Dilutions

• Dilutions:
  • ELISA
  • Flow Cytometry
  • Immunocytochemistry/ Immunofluorescence
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Protein A purified

Notes

Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for ACOT8 Antibody (4D10) [Janelia Fluor® 669]

• ACTEIII
• acyl-CoA thioesterase 8HNAACTE
• Choloyl-coenzyme A thioesterase
• EC 3.1.2.27
• hACTEIII
• HIV-Nef-associated acyl-CoA thioesterase
• hTEcholoyl-CoA hydrolase
• long-chain fatty-acyl-CoA hydrolase
• palmitoyl-CoA hydrolase
• peroxisomal acyl-CoA thioesterase 1
• peroxisomal acyl-CoA thioesterase
• Peroxisomal acyl-coenzyme A thioester hydrolase 1
• Peroxisomal long-chain acyl-CoA thioesterase 1
• PTE-1
• PTE1HIV-Nef associated acyl-CoA thioesterase
• PTE2
• PTE-2hACTE-IIIacyl-coenzyme A thioesterase 8
• Thioesterase II
• thioesterase III

Background

ACOT8 is encoded by this gene is a peroxisomal thioesterase that appears to be involved more in the oxidation of fatty acids rather than in their formation. The encoded protein can bind to the human immunodeficiency virus-1 protein Nef, and mediate Nef-induced down-regulation of CD4 in T-cells. Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: ACOT8