Abraxas Antibody (ABRA1-01)

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Immunohistochemistry-Paraffin: Abraxas Antibody (ABRA1-01) [NBP1-69762] - Analysis of anti-FAM175A / CCDC98 antibody with human testis at concentration 10 ug/ml.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, Flow, IHC-P, IP
Clone
ABRA1-01
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated
Concentration
1.0 mg/ml

Order Details

Abraxas Antibody (ABRA1-01) Summary

Immunogen
Recombinant protein corresponding to amino acids 1-313 of ABRA1 with N-terminal His6 tag.
Specificity
The mouse monoclonal antibody ABRA1-01 recognizes N-terminal part of ABRA1 (Abraxas, CCDC98), an adaptor protein involved in DNA repair, which migrates as a 45 kD band on PAAGE under reducing conditions.
Isotype
IgG
Clonality
Monoclonal
Host
Mouse
Gene
FAM175A
Purity
Protein A purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1:100-1:2000
  • Flow Cytometry 1 - 2 ug/ml
  • Immunohistochemistry-Paraffin 10 ug/ml
  • Immunoprecipitation 1:10-1:500

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.4)
Preservative
15mM Sodium Azide
Concentration
1.0 mg/ml
Purity
Protein A purified

Alternate Names for Abraxas Antibody (ABRA1-01)

  • BRCA1-A complex subunit Abraxas
  • ABRA1
  • CCDC98
  • family with sequence similarity 175, member A

Background

Abraxas was identified in a phosphopeptide affinity proteomic and mass spec analysis as a protein that bound directly to the BRCA1 BRCT repeat. Along with RAP80, Abraxas was required to form a complex with BRCA1 for the DNA damage response.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol FAM175A
Entrez
Uniprot