ABI1 Antibody (1013203) [Alexa Fluor® 488]

• Reactivity: Hu
• Applications: IHC, ICC/IF
• Clone: 1013203
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Alexa Fluor 488

ABI1 Antibody (1013203) [Alexa Fluor® 488] Summary

• Immunogen: E. coli-derived recombinant human ABI1
  Val429-Asp508
  Accession # Q8IZP0
• Specificity: Detects human ABI1 in direct ELISAs.
• Isotype: IgG2b
• Clonality: Monoclonal
• Host: Mouse
• Purity Statement: Protein A or G purified

Applications/Dilutions

• Dilutions:
  • Immunocytochemistry
  • Immunohistochemistry

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
• Buffer: Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for ABI1 Antibody (1013203) [Alexa Fluor® 488]

• Abelson interactor 1
• ABI1
• ABI-1
• abl interactor 1
• Abl-binding protein 4
• ABLBP4
• abl-interactor 1
• Abl-interactor protein 1 long
• E3B1
• eps8 binding protein
• Eps8 SH3 domain-binding protein
• Eps8-binding protein
• interactor protein AblBP4
• nap1 binding protein
• Nap1-binding protein
• NAP1BP
• spectrin SH3 domain binding protein 1
• Spectrin SH3 domain-binding protein 1
• SSH3BP
• SSH3BP1

Background

Abelson Interactor 1 (ABI1) is an adaptor protein involved in cytoskeletal reorganization and EGFR signaling. Overexpression of ABI1 inhibits EGF-induced activation of Erks which negatively regulate cell growth and transformation. In the brain, ABI1 seems to regulate dendritic outgrowth and determines the shape and number of synaptic contacts of developing neurons.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.