ABH1 Antibody (OTI4C4)

Immunohistochemistry: ABH1 Antibody (4C4) [NBP2-46511] - Analysis of Carcinoma of Human lung tissue.(Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120C for 3min)

Immunohistochemistry: ABH1 Antibody (4C4) [NBP2-46511] - Analysis of Human tonsil tissue. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120C for 3min)

• Reactivity: Hu
• Applications: IHC
• Clone: OTI4C4
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Unconjugated
• Concentration: 1 mg/ml

ABH1 Antibody (OTI4C4) Summary

• Description: Novus Biologicals Mouse ABH1 Antibody (OTI4C4) (NBP2-46511) is a monoclonal antibody validated for use in IHC. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: Human recombinant protein fragment corresponding to amino acids 1-245 of human ALKBH1 (NP_006011) produced in E.coli.
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Gene: ALKBH1
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry 1:150
  • Immunohistochemistry-Paraffin
• Theoretical MW: 43.7 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.3), 1.0% BSA and 50% Glycerol
• Preservative: 0.02% Sodium Azide
• Concentration: 1 mg/ml
• Purity: Immunogen affinity purified

Alternate Names for ABH1 Antibody (OTI4C4)

• ABH1
• ABHalkB, alkylation repair homolog (E. coli)
• alkB
• alkB, alkylation repair homolog 1 (E. coli)
• ALKBH
• alkylated DNA repair protein alkB homolog 1
• alkylation repair, alkB homolog
• Alpha-ketoglutarate-dependent dioxygenase ABH1
• DNA lyase ABH1
• EC 1.14.11.-
• EC 4.2.99.18
• hABH

Background

ABH1 encodes a homolog to the E. coli alkB gene product. The E. coli alkB protein is part of the adaptive response mechanism of DNA alkylation damage repair. It is involved in damage reversal by oxidative demethylation of 1-methyladenine and 3-methylcytosine.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: ALKBH1