ABCA6 Antibody

Product Discontinued

ABCA6 Antibody Summary

• Immunogen: Peptide with sequence C-RWKLLPHSDEP corresponding to C-Terminus according to NP_525023.2.
• Epitope: C terminus
• Isotype: IgG
• Clonality: Polyclonal
• Host: Goat
• Gene: ABCA6
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Peptide ELISA Detection limit 1:32000
• Application Notes: WB: Preliminary experiments gave an approx. 50 kDa band in human brain (cerebellum, cerebral cortex, frontal cortex) lysates after 0.5 ug/ml antibody staining. Please note that currently we cannot find an explanation in the literature for the band we observe given the calculated size of 184 kDa band according to NP_525023.2. The 50 kDa band was successfully blocked by incubation with the immunizing peptide.

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA
• Preservative: 0.02% Sodium Azide
• Concentration: 0.5 mg/ml
• Purity: Immunogen affinity purified

Notes

Please note, this antibody is considered Innovators Grade. Innovators Grade antibodies are generally unvalidated and require additional characterization for most new species/applications. Novus has made these antibodies available through our Innovators Reward program. Complete an online review with image, detailing your positive or negative results. In return, you receive a discount voucher for 100% of the purchase price of the reviewed product. Please contact us at innovators@novusbio.com for more details.

Alternate Names for ABCA6 Antibody

• ABC transporter ABCA6
• ATP-binding cassette A6
• ATP-binding cassette sub-family A member 6
• ATP-binding cassette, sub-family A (ABC1), member 6
• EC 2.5.1.19
• EC 3.6.3
• EC 3.6.3.25
• EST155051
• FLJ43498

Background

The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, and White). This encoded protein is a member of the ABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes. This gene is clustered among 4 other ABC1 family members on 17q24 and may play a role in macrophage lipid homeostasis.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for ABCA6 Antibody (NBP1-20866)(1)

Publication using NBP1-20866

• Kaminski WE, Wenzel JJ, Piehler A et al. ABCA6, a novel a subclass ABC transporter. Biochem Biophys Res Commun 2001-08-03 [PMID: 11478798]

Bioinformatics

• Gene Symbol: ABCA6
• Entrez:
  • 23460(Human)
• Uniprot:
  • NP_525023.2(Human)