5-HT7 Antibody Blocking Peptide

• Reactivity: Hu
• Applications: AC
• Concentration: LYOPH

5-HT7 Antibody Blocking Peptide Summary

• Description: A 5-HT7 antibody blocking peptide.
• Immunogen: A synthetic peptide from aa region 300-350 of human 5HT7 R conjugated to blue carrier protein was used as the antigen. The peptide is homologous in rat, mouse and guinea pig.
• Protein/Peptide Type: Antibody Blocking Peptide
• Gene: HTR7

Applications/Dilutions

• Dilutions:
  • Antibody Competition
• Application Notes: This peptide is useful as a blocking peptide for NBP1-46598. For further blocking peptide related protocol, click here.

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Concentration: LYOPH
• Reconstitution Instructions: Reconstitute to desired concentration using sterile water. Centrifuge to remove any insoluble material. Glycerol may be added (1:1) for additional stability.

Notes

This item will be shipped to you at ambient temperature in a lyophilised form.

Alternate Names for 5-HT7 Antibody Blocking Peptide

• 5HT7
• 5-HT7
• 5-HT-7
• 5-HT75-hydroxytryptamine receptor 7
• 5-HT-X
• 5-hydroxytryptamine (serotonin) receptor 7 (adenylate cyclase-coupled)
• HTR7
• serotonin 5-HT-7 receptor
• Serotonin receptor 7

Background

Receptors for serotonin (5-hydroxytryptamine, 5-HT) are classified into seven major classes (5-HTR1-7), based on structural, functional and pharmacological criteria (Hoyer et al, 1994). The 5-HT7 receptor (5-HT7R) is a seven-transmembrane-domain G-protein-coupled receptor that has important roles in regulating diverse biological process in the central and peripheral nervous systems (reviewed in Hedlund and Sutcliffe, 2004). Receptors for serotonin (5-hydroxytryptamine, 5-HT) are classified into seven major classes (5-HT1-7), based on structural, functional and pharmacological criteria (Hoyer et al, 1994). Sequence alignment shows a high degree of interspecies 5-HT7R homology (>90%), and a low homology with other 5-HTRs (

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

Bioinformatics

• Gene Symbol: HTR7