5-HT2A Antibody (1055217) [Alexa Fluor® 750]

• Reactivity: Hu
• Applications: WB, Flow, ICC/IF
• Clone: 1055217
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Alexa Fluor 750

5-HT2A Antibody (1055217) [Alexa Fluor® 750] Summary

• Immunogen: Synthetic peptide corresponding to the amino acids 1-75 in the N-term extracellular domain of the Serotonin Receptor 5-HT2A (HTR2A).
  Accession # P28223
• Specificity: Detects Human HTR2A in Direct ELISA. In flow cytometry, it detects Human HTR2A in HEK293 tranfected cells but it does not detect parental HEK293 or mock irrelevant transfectants.
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Purity Statement: Protein A or G purified

Applications/Dilutions

• Dilutions:
  • Flow Cytometry
  • Immunocytochemistry
  • Western Blot

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
• Buffer: Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for 5-HT2A Antibody (1055217) [Alexa Fluor® 750]

• 5-HT2 receptor
• 5-HT-2
• 5HT2A
• 5-HT2A
• 5-HT-2A
• 5-hydroxytryptamine (serotonin) receptor 2A
• 5-hydroxytryptamine receptor 2A
• HTR2,5-HT2A
• HTR2A
• serotonin 5-HT-2A receptor
• Serotonin receptor 2A

Background

Human serotonin receptor HTR2A, also known as 5-HT2A or HTR2, is a G-protein coupled receptor (GPCR) for 5-hydroxytryptamine (serotonin). The 5-HT2A receptor is mainly a cell surface receptor with several intracellular locations. Human -5-HT2A is the main excitatory receptor subtype among the GPCRs for serotonin but an inhibitory effect on the visual cortex and the orbitofrontal cortex has also been described. This receptor was first noted for its importance as a target of serotonergic psychedelic drugs such as LSD and psilocybin mushrooms.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.