5-HT1E Antibody (HL3875)

Non-transfected (-) and transfected (+) unboiled 293T whole cell extracts (30 ug) were separated by 10% SDS-PAGE, and the membrane was blotted with 5-HT1E antibody [HL3875] (NBP3-48852) diluted at 1:5000. The HRP-conjugated anti-rabbit IgG antibody was used to detect the primary antibody.

5-HT1E antibody [HL3875] detects 5-HT1E protein by immunohistochemical analysis.Sample: Paraffin-embedded human tissues.5-HT1E stained by 5-HT1E antibody [HL3875] (NBP3-48852) diluted at 1:200.Antigen Retrieval: Tris-EDTA buffer, pH 9.0, 15 min

• Reactivity: Hu
• Applications: WB
• Clone: HL3875
• Clonality: Monoclonal
• Host: Rabbit
• Conjugate: Unconjugated

5-HT1E Antibody (HL3875) Summary

• Description: Novus Biologicals Rabbit 5-HT1E Antibody (HL3875) (NBP3-48852) is a recombinant monoclonal antibody validated for use in WB. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Additional Information: Recombinant Monoclonal Antibody
• Immunogen: Recombinant protein encompassing a sequence within the Intracellular domain of human 5-HT1E. The exact sequence is proprietary.
• Isotype: IgG
• Clonality: Monoclonal
• Host: Rabbit
• Gene: HTR1E
• Purity: Protein A purified

Applications/Dilutions

• Dilutions:
  • Western Blot

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS
• Preservative: No Preservative
• Purity: Protein A purified

Alternate Names for 5-HT1E Antibody (HL3875)

• 5HT1E
• 5-HT1E
• 5-HT-1E
• 5-hydroxytryptamine (serotonin) receptor 1E
• HTR1E
• S31
• S31,5-HT1E5-hydroxytryptamine receptor 1E
• Serotonin receptor 1E

Background

5HT1E Receptor, also known as 5-hydroxytryptamine receptor 1E, is a 365 amino acid protein that is 42 kDa, belongs to the G-protein coupled receptor 1 family, has cell membrane intracellular location; commonly found in the cortex, caudate putamen, claustrum, hippocampus, and amygdala; is one of the many different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that plays a role of a neurotransmitter, a hormone, and a mitogen; this receptor activity is mediated by G proteins that inhibit adenylate cyclase activity. The protein is being studied for its involvement in attention deficit hyperactivity disorder, autism spectrum disorder, chronic fatigue syndrome, hermaphroditism, pharyngitis, neuronitis, and skin papilloma. This protein has been linked to the GPCR downstream signaling, GPCR ligand binding, class A/1 (Rhodopsin-like receptors), serotonin receptors, amine ligand-binding receptors, intracellular calcium signaling, signal transduction, G alpha (i) signaling events, neuroactive ligand-receptor interaction, and amine ligand-binding receptors pathways where it interacts with PSMC3, PSMC4, ADORA3, ADORA1, ADRA2A, APP, CCR3 and over 100 other proteins.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: HTR1E