mTOR Signaling and the Tumor Microenvironment

The Many Connections Between Autophagy and Kidney Disease

Potential therapies for human ovarian cancer surrounding the PI3K/AKT/mTOR pathway

Mammalian target of Rapamycin (mTOR) is a serine/threonine kinase that regulates cell growth, proliferation, motility and survival.

Thomson Reuters Predicts 2016 Nobel Prize Winners

Here at Bio-Techne we always look forward to the annual announcements of winners of the highly coveted Nobel Prize – the greatest award in science. How can you go about predicting which scientists might be in line for a life-changing phone-call from the Nobel Committee?

Well, looking at citations is one possible approach.

mTOR - a central regulator of cell metabolism

The mammalian target of rapamycin (mTOR) signaling pathway allows cells to monitor environmental signals like nutrient availability and oxygen levels. mTOR is a phosphoinositide 3-kinase (PI3K)-related protein that assembles into large protein complexes (mTORC1 and mTORC2) capable of regulating cell metabolism, growth, and proliferation.