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Adenosine Deaminase/ADA Antibody (EPR4438)

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Summary
Product Discontinued
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    • Catalog Number
      NBP1-95477
    • Availability
      Product Discontinued

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Adenosine Deaminase/ADA Antibody (EPR4438) Summary

Immunogen
A synthetic peptide corresponding to residues in human ADA was used as an immunogen.
Clonality
Monoclonal
Host
Rabbit
Gene
ADA
Purity
Tissue culture supernatant
Innovator's Reward
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Applications/Dilutions

Dilutions
  • Immunocytochemistry/ Immunofluorescence 1:250-500
  • Immunoprecipitation 1:10-100
  • Western Blot 1:1000-10000
Theoretical MW
41 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Reactivity Notes

Reacts with: Rat, Human Does not react with Mouse

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Buffer
49% PBS, 0.05% BSA and 50% Glycerol
Preservative
0.01% Sodium Azide
Purity
Tissue culture supernatant

Notes

Produced using Abcam's RabMab® technology. RabMab® technology is covered by the following U.S. Patents, No. 5,675,063 and/or 7,429,487.

Alternate Names for Adenosine Deaminase/ADA Antibody (EPR4438)

  • ADA
  • ADA1
  • adenine deaminase
  • Adenosine aminohydrolase
  • Adenosine Deaminase
  • EC 3.5.4.4

Background

ADA is an enzyme that catalyzes the hydrolysis of adenosine to inosine. Various mutations have been described for this protein and have been linked to human diseases. Deficiency in this enzyme causes a form of severe combined immunodeficiency disease (SCID), in which there is dysfunction of both B and T lymphocytes with impaired cellular immunity and decreased production of immunoglobulins, whereas elevated levels of this enzyme have been associated with congenital hemolytic anemia (1).

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol ADA
Entrez
Uniprot