ZFYVE9 Antibody Pair

Product Discontinued

ZFYVE9 Antibody Pair Summary

• Description: Quality control test: Immunoprecipitation-Western Blot (IP-WB). This IP-WB antibody pair set comes with one antibody for immunoprecipitation and another to detect the precipitated protein in western blot.
  
  
• Antibody pair for IP: rabbit polyclonal anti-ZFYVE9 (300 ul)
• Antibody pair for WB: rabbit polyclonal anti-ZFYVE9 (50 ul)
• Clonality: Polyclonal
• Gene: ZFYVE9
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunoprecipitation
  • Western Blot

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: 1x PBS, pH 7.4
• Preservative: No Preservative
• Purity: Immunogen affinity purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for ZFYVE9 Antibody Pair

• Madh-interacting protein
• MADHIP
• mothers against decapentaplegic homolog interacting protein
• mothers against decapentaplegic homolog interacting protein, receptoractivation anchor
• NSP
• receptor activation anchor
• SARAhSARA
• Smad anchor for receptor activation
• SMADIPMAD, mothers against decapentaplegic homolog (Drosophila) interacting protein
• zinc finger FYVE domain-containing protein 9
• zinc finger, FYVE domain containing 9

Background

ZFYVE9 encodes a double zinc finger (FYVE domain) protein that interacts directly with SMAD2 and SMAD3, and is involved in Alzheimer's disease. SMAD proteins transmit signals from transmembrane serine/threonine kinase receptors to the nucleus. The FYVE domain has been identified in a number of unrelated signaling molecules. This protein functions to recruit SMAD2 to the transforming growth factor-beta receptor. The FYVE domain is required to maintain the normal localization of this protein but is not involved in mediating interaction with SMADs. The C-terminal domain of this protein interacts with the TGFB receptor. This protein is a component of the TGFB pathway that brings the SMAD substrate to the receptor. Three alternatively spliced transcripts encoding distinct isoforms have been found for this gene. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Antibody Pairs are guaranteed for 6 months from date of receipt.

Bioinformatics

• Gene Symbol: ZFYVE9