YAF2 Antibody [Janelia Fluor® 646]

• Reactivity: Hu
• Applications: WB, IP
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Janelia Fluor 646

YAF2 Antibody [Janelia Fluor® 646] Summary

• Immunogen: The immunogen recognized by this antibody maps to a region between residue 50 and 100 of human YY1 Associated Factor 2 using the numbering given in entry NP_005739.2 (GeneID 10138).
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: YAF2
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunoprecipitation
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Immunogen affinity purified

Notes

Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for YAF2 Antibody [Janelia Fluor® 646]

• DKFZp779H1820
• MGC41856
• YY1 associated factor 2
• YY1-associated factor 2

Background

The protein encoded by the YAF2 gene interacts with YY1, a zinc finger protein involved in negative regulation ofmuscle-restricted genes. This gene product itself contains a single N-terminal C2-X10-C2 zinc finger, and in contrastto YY1, is up-regulated during myogenic differentiation. It also facilitates proteolytic cleavage of YY1 by thecalcium- activated protease, m-calpain, suggesting a mechanism by which this protein antagonizes the negative effectof YY1. (provided by RefSeq)

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: YAF2