XRCC4 Antibody

Western Blot: XRCC4 Antibody [H00007518-D01P] - Analysis of XRCC4 expression in mouse liver.

Western Blot: XRCC4 Antibody [H00007518-D01P] - Analysis of XRCC4 expression in transfected 293T cell line by XRCC4 polyclonal antibody.Lane 1: XRCC4 transfected lysate(38.30 KDa).Lane 2: Non-transfected lysate.

Product Discontinued

XRCC4 Antibody Summary

• Description: Quality control test: Antibody reactive against mammalian transfected lysate.
• Immunogen: XRCC4 (NP_071801.1, 1 a.a. - 336 a.a.) full-length human protein. MERKISRIHLVSEPSITHFLQVSWEKTLESGFVITLTDGHSAWTGTVSESEISQEADDMAMEKGKYVGELRKALLSGAGPADVYTFNFSKESCYFFFEKNLKDVSFRLGSFNLEKVENPAEVIRELICYCLDTIAENQAKNEHLQKENERLLRDWNDVQGRFEKCVSAKEALETDLYKRFILVLNEKKTKIRSLHNKLLNAAQEREKDIKQEGETAICSEMTADRDPVYDESTDEESENQTDLSGLASAAVSKDDSIISSLDVTDIAPSRKRRQRMQRNLGTEPKMAPQENQLQEKENSRPDSSLPETSKKEHISAENMSLETLRNSSPEDLFDEI
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: XRCC4
• Purity: Protein G purified

Applications/Dilutions

• Dilutions:
  • Western Blot
• Application Notes: It has been used for WB.

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.4)
• Preservative: No Preservative
• Purity: Protein G purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for XRCC4 Antibody

• complementing defective, repair in Chinese hamster
• X-ray repair complementing defective repair in Chinese hamster cells 4
• X-ray repair cross-complementing protein 4

Background

The protein encoded by this gene functions together with DNA ligase IV and the DNA-dependent protein kinase in the repair of DNA double-strand break by non-homologous end joining and the completion of V(D)J recombination events. The non-homologous end-joining pathway is required both for normal development and for suppression of tumors. This gene functionally complements XR-1 Chinese hamster ovary cell mutant, which is impaired in DNA double-strand breaks produced by ionizing radiation and restriction enzymes. This gene contains 8 exons, and alternative transcription initiation and alternative splicing generates several transcript variants.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: XRCC4
• Uniprot:
  • NP_071801.1(Human)