XRCC4 Products

Antibodies
XRCC4 Antibody (4H9)
XRCC4 Antibody (4H9)
Species: Hu
Applications: WB, IHC, IHC-P
Host: Mouse Monoclonal
XRCC4 Antibody
XRCC4 Antibody
NBP1-89463
Species: Hu
Applications: WB, ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
XRCC4 Antibody
XRCC4 Antibody
NBP1-31339
Species: Hu
Applications: WB, ICC/IF, IHC, IHC-P, IP
Host: Rabbit Polyclonal
Antibody Pairs
XRCC4 Antibody Pair
XRCC4 Antibody Pair
H00007518-AP21
Species: Hu
Applications: S-ELISA
XRCC4 Antibody Pair
XRCC4 Antibody Pair
H00007518-PW1
Species: Hu
Applications: WB, IP
Lysates
XRCC4 Overexpression Lysate ( ...
XRCC4 Overexpression Lysate (Denat...
H00007518-T01
Species: Hu
Applications: WB
XRCC4 Overexpression Lysate ( ...
XRCC4 Overexpression Lysate (Native)
NBP2-08016
Applications: WB
XRCC4 Overexpression Lysate ( ...
XRCC4 Overexpression Lysate (Native)
NBL1-17916
Applications: WB
Proteins
XRCC4 Partial Recombinant Pro ...
XRCC4 Partial Recombinant Protein
H00007518-Q01
Species: Hu
Applications: WB, ELISA, PA
XRCC4 Recombinant Protein
XRCC4 Recombinant Protein
H00007518-P01
Species: Hu
Applications: WB, ELISA, PA
XRCC4 Recombinant Protein Ant ...
XRCC4 Recombinant Protein Antigen
NBP1-89463PEP
Species: Hu
Applications: AC

Description

XRCC4 is encoded by this gene functions together with DNA ligase IV and the DNA-dependent protein kinase in the repair of DNA double-strand break by non-homologous end joining and the completion of V(D)J recombination events. The non-homologous end-joining pathway is required both for normal development and for suppression of tumors. This gene functionally complements XR-1 Chinese hamster ovary cell mutant, which is impaired in DNA double-strand breaks produced by ionizing radiation and restriction enzymes. Alternative transcription initiation and alternative splicing generates several transcript variants. [provided by RefSeq]

Bioinformatics

Entrez Human
Uniprot Human
Human
Human
Human
Product By Gene ID 7518
Alternate Names
  • complementing defective, repair in Chinese hamster
  • X-ray repair cross-complementing protein 4
  • X-ray repair complementing defective repair in Chinese hamster cells 4

Research Areas for XRCC4

Find related products by research area and learn more about each of the different research areas below.

Cancer
DNA Double Strand Break Repair
DNA Repair
Homologous Recombination
Non-homologous end-joining
Tumor Suppressors

Bioinformatics Tool for XRCC4

Discover related pathways, diseases and genes to XRCC4. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
Vizit™, under license from BioVista Inc.

Related XRCC4 Blog Posts

Check out the latest blog posts on XRCC4.
Ku70: The DNA's Mr. Fix-it
Ku70, known by several synonyms including X-ray repair cross-complementing, 5'-deoxyribose-5-phosphate lyase Ku70 protein 6, 70 kDa subunit of Ku antigen, XRCC6, and G22P1, is a 70 kDa protein that was shown to be involved in multiple cellular pathway...    Read more.
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