XRCC4 Antibody Pair

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Summary
Product Discontinued
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    • Catalog Number
      H00007518-AP21
    • Availability
      Product Discontinued

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XRCC4 Antibody Pair Summary

Description
Quality control test: Standard curve using recombinant protein (H00007518-P01) as an analyte. This antibody pair set comes with matched antibody pair to detect and quantify protein level of human XRCC4.

  • Capture antibody: rabbit MaxPab affinity purified polyclonal anti-XRCC4 (100 ug)
  • Detection antibody: mouse purified polyclonal anti-XRCC4 (20 ug)
  • Standard Curve Range
    0.3 ng/ml to 100 ng/ml
    Assay Type
    Sandwich ELISA
    Clonality
    Monoclonal
    Gene
    XRCC4

    Applications/Dilutions

    Dilutions
    • Sandwich ELISA 0.3 ng/ml - 100 ng/ml

    Packaging, Storage & Formulations

    Storage
    Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
    Buffer
    1x PBS, pH 7.4
    Preservative
    No Preservative

    Notes

    This product is produced by and distributed for Abnova, a company based in Taiwan.

    Alternate Names for XRCC4 Antibody Pair

    • complementing defective, repair in Chinese hamster
    • X-ray repair complementing defective repair in Chinese hamster cells 4
    • X-ray repair cross-complementing protein 4

    Background

    XRCC4 is encoded by this gene functions together with DNA ligase IV and the DNA-dependent protein kinase in the repair of DNA double-strand break by non-homologous end joining and the completion of V(D)J recombination events. The non-homologous end-joining pathway is required both for normal development and for suppression of tumors. This gene functionally complements XR-1 Chinese hamster ovary cell mutant, which is impaired in DNA double-strand breaks produced by ionizing radiation and restriction enzymes. Alternative transcription initiation and alternative splicing generates several transcript variants. [provided by RefSeq]

    Limitations

    This product is for research use only and is not approved for use in humans or in clinical diagnosis. Antibody Pairs are guaranteed for 6 months from date of receipt.

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    Blogs on XRCC4.

    Ku70: The DNA's Mr. Fix-it
    Ku70, known by several synonyms including X-ray repair cross-complementing, 5'-deoxyribose-5-phosphate lyase Ku70 protein 6, 70 kDa subunit of Ku antigen, XRCC6, and G22P1, is a 70 kDa protein that was shown to be involved in multiple cellular pathway...  Read full blog post.

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    Bioinformatics

    Gene Symbol XRCC4