Wnt-7b Antibody [PerCP]

• Reactivity: Hu
• Applications: IHC
• Clonality: Polyclonal
• Host: Goat
• Conjugate: PerCP

Wnt-7b Antibody [PerCP] Summary

• Immunogen: E. coli-derived recombinant human Wnt‑7b
  Leu32-Glu72 & Thr216-Ala283
  Accession # P56706
• Specificity: Detects human Wnt-7b in direct ELISAs.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Goat
• Gene: WNT7B
• Purity: Antigen Affinity-purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: PBS
• Preservative: 0.05% Sodium Azide
• Purity: Antigen Affinity-purified

Alternate Names for Wnt-7b Antibody [PerCP]

• protein Wnt-7b
• wingless-type MMTV integration site family, member 7B
• Wnt7b
• Wnt-7b

Background

Wnt7b is a gene that codes for a protein that is 349 amino acids in length and approximately 39 kDa in weight that is a ligand for members of the frizzled family of transmembrane receptors that may function to facilitate the development of discrete region of tissues. Current studies are being done on several diseases and disorders linked to this gene including carcinoma, leukemia, fainting, hermaphroditism, melanoma, prostatitis, neuronitis, and colorectal cancer. Wnt7b has also been shown to have interactions with FZD1, FZD10, FZD5, GPC3, and LRP5 in pathways such as the GSK3 signaling, colorectal cancer metastasis, DNA damage response, and GPCR ligand binding pathways.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: WNT7B