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VC004). Before incubation with the primary antibody, tissue was subjected to heat-induced epitope retrieval using VisUCyte Antigen Retrieval Reagent-Basic (Catalog # VCTS021). Tissue was stained using DAB (brown) and counterstained with hematoxylin (blue). Specific staining was localized to cell surface and cytoplasm of cancer cells. View our protocol for IHC Staining with VisUCyte HRP Polymer Detection Reagents." class="big_lightbox" target="_blank">
Wnt7b is a gene that codes for a protein that is 349 amino acids in length and approximately 39 kDa in weight that is a ligand for members of the frizzled family of transmembrane receptors that may function to facilitate the development of discrete region of tissues. Current studies are being done on several diseases and disorders linked to this gene including carcinoma, leukemia, fainting, hermaphroditism, melanoma, prostatitis, neuronitis, and colorectal cancer. Wnt7b has also been shown to have interactions with FZD1, FZD10, FZD5, GPC3, and LRP5 in pathways such as the GSK3 signaling, colorectal cancer metastasis, DNA damage response, and GPCR ligand binding pathways.
![Immunohistochemistry Wnt-7b Antibody [Unconjugated]](http://images.novusbio.com/images/antibody/af3460_human-wnt-7b-affinity-purified-polyclonal-ab-immunohistochemistry-12122023155533..jpg)
![Immunocytochemistry/ Immunofluorescence Wnt-7b Antibody [Unconjugated]](http://images.novusbio.com/fullsize/af3460_human-wnt-7b-affinity-purified-polyclonal-ab-immunocytochemistry-immunofluorescence-12122025815222.jpg)
