VPS26A Antibody (JB93-41)

Western Blot: VPS26A Antibody (JB93-41) [NBP2-75709] - Analysis of VPS26 on different cell lysates using anti-VPS26 at 1/500 dilution.Positive control:Line 1: Rat kidney tissue Line 2: A431

Immunohistochemistry-Paraffin: VPS26A Antibody (JB93-41) [NBP2-75709] - Analysis of paraffin-embedded rat kidney tissue using anti-VPS26 antibody. Counter stained with hematoxylin.

Immunohistochemistry-Paraffin: VPS26A Antibody (JB93-41) [NBP2-75709] - Analysis of paraffin-embedded human tonsil tissue using anti-VPS26 antibody. Counter stained with hematoxylin.

Immunohistochemistry-Paraffin: VPS26A Antibody (JB93-41) [NBP2-75709] - Analysis of paraffin-embedded mouse testis tissue using anti-VPS26 antibody. Counter stained with hematoxylin.

Product Discontinued

VPS26A Antibody (JB93-41) Summary

• Additional Information: Recombinant Monoclonal Antibody.
• Immunogen: Recombinant protein within Human VPS26A aa 210-327 / 327. (SwissProt: O75436 Human; SwissProt: P40336 Mouse; SwissProt: Q6AY86 Rat)
• Localization: Endosome. Cytoplasm.
• Isotype: IgG
• Clonality: Monoclonal
• Host: Rabbit
• Gene: VPS26A
• Purity: Protein A purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin 1:50-1:200
  • Immunoprecipitation 1:10-1:50
  • Western Blot 1:500-1:2000
• Theoretical MW: 38 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: TBS (pH7.4), 0.05% BSA, 40% Glycerol
• Preservative: 0.05% Sodium Azide
• Concentration: 1 mg/ml
• Purity: Protein A purified

Alternate Names for VPS26A Antibody (JB93-41)

• FLJ12930
• HB58
• Hbeta58
• hVPS26
• PEP8A
• vacuolar protein sorting 26 (yeast homolog)
• vacuolar protein sorting 26 homolog A (S. pombe)
• vacuolar protein sorting 26 homolog A (yeast)
• vacuolar protein sorting-associated protein 26A
• Vesicle protein sorting 26A
• VPS26vacuolar protein sorting 26 (yeast)

Background

VPS26 belongs to a group of vacuolar protein sorting (VPS) genes. The encoded protein is a component of a large multimeric complex, termed the retromer complex, involved in retrograde transport of proteins from endosomes to the trans-Golgi network. The close structural similarity between the yeast and human proteins that make up this complex suggests a similarity in function. Expression studies in yeast and mammalian cells indicate that this protein interacts directly with VPS35, which serves as the core of the retromer complex.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: VPS26A