Vang-like Protein 2/VANGL2 Antibody

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Western Blot: Vang-like Protein 2/VANGL2 Antibody [NB100-59736] - Staining of mouse brain lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Product Details

Summary
Reactivity MuSpecies Glossary
Applications WB, PEP-ELISA
Clonality
Polyclonal
Host
Goat
Conjugate
Unconjugated
Concentration
0.5 mg/ml

Order Details

Vang-like Protein 2/VANGL2 Antibody Summary

Immunogen
Peptide with sequence C-QKYLRTTKQQPYH corresponding to internal region according to NP_065068.1.
Epitope
QKYLRTTKQQPYH
Isotype
IgG
Clonality
Polyclonal
Host
Goat
Gene
VANGL2
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Western Blot 0.3 - 1 ug/ml
  • Peptide ELISA Detection limit 1:32000
Application Notes
WB: Approx 55 kDa band observed in mouse brain lysates (calculated MW of 59.7kDa according to NP_065068.1).
Positive Control
Brain Lysate (NB820-59657)
Publications
Read Publication using NB100-59736.

Reactivity Notes

Predicted cross-reactivity based on sequence identity: Human, Bovine, Zebrafish.

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Buffer
0.5 mg/ml Tris (pH 7.3) and 0.5% BSA
Preservative
0.02% Sodium Azide
Concentration
0.5 mg/ml
Purity
Immunogen affinity purified

Alternate Names for Vang-like Protein 2/VANGL2 Antibody

  • KIAA1215Loop-tail protein 1 homolog
  • loop-tail-associated protein
  • LPP1
  • LTAP
  • LTAPVan Gogh-like protein 2
  • MGC119403
  • MGC119404
  • STB1
  • STB1Strabismus 1
  • STBM
  • STBM1
  • Strabismus
  • vang (van gogh, Drosophila)-like 2, vang, van gogh-like 2 (Drosophila)
  • Vang like Protein 2
  • VANGL2
  • vang-like 2 (van gogh, Drosophila)
  • Vang-like Protein 2

Background

VANGL2 is involved in the control of early morphogenesis and patterning of both axial midline structures and the development of neural plate. It plays a role in the regulation of planar cell polarity, particularly in the orientation of stereociliary bundles in the cochlea. It is required for polarization and movement of myocardializing cells in the outflow tract and seems to act via RHOA signaling to regulate this process. The VANGL2 gene encodes a homolog of Drosophila 'strabismus/Van Gogh' (Stbm/Vang), a component of the frizzled-dishevelled tissue polarity pathway.[supplied by OMIM]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for Vang-like Protein 2/VANGL2 Antibody (NB100-59736)(1)

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Positive Control Lysate(s)

Secondary Antibodies

 

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Bioinformatics

Gene Symbol VANGL2
Entrez
Uniprot