Vang-like Protein 2/VANGL2 Antibody [PerCP]

• Reactivity: Hu, Mu, Rt
• Applications: WB, IHC, IP, ICC/IF
• Clonality: Polyclonal
• Host: Sheep
• Conjugate: PerCP

Vang-like Protein 2/VANGL2 Antibody [PerCP] Summary

• Immunogen: E. coli-derived recombinant human Vang-like Protein 2/VANGL2
  Gln241-Val521
  Accession # Q9ULK5
• Specificity: Detects human, mouse, and rat Vang-like Protein 2/VANGL2 in direct ELISAs and Western blots. In direct ELISAs, approximately 10% cross-reactivity with recombinant human VANGL1 is observed.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Sheep
• Gene: VANGL2
• Purity: Antigen Affinity-purified

Applications/Dilutions

• Dilutions:
  • Immunocytochemistry
  • Immunohistochemistry
  • Immunohistochemistry-Frozen
  • Immunoprecipitation
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: PBS
• Preservative: 0.05% Sodium Azide
• Purity: Antigen Affinity-purified

Alternate Names for Vang-like Protein 2/VANGL2 Antibody [PerCP]

• KIAA1215Loop-tail protein 1 homolog
• loop-tail-associated protein
• LPP1
• LTAP
• LTAPVan Gogh-like protein 2
• MGC119403
• MGC119404
• STB1
• STB1Strabismus 1
• STBM
• STBM1
• Strabismus
• vang (van gogh, Drosophila)-like 2, vang, van gogh-like 2 (Drosophila)
• Vang like Protein 2
• VANGL2
• vang-like 2 (van gogh, Drosophila)
• Vang-like Protein 2

Background

VANGL2 is involved in the control of early morphogenesis and patterning of both axial midline structures and the development of neural plate. It plays a role in the regulation of planar cell polarity, particularly in the orientation of stereociliary bundles in the cochlea. It is required for polarization and movement of myocardializing cells in the outflow tract and seems to act via RHOA signaling to regulate this process. The VANGL2 gene encodes a homolog of Drosophila 'strabismus/Van Gogh' (Stbm/Vang), a component of the frizzled-dishevelled tissue polarity pathway.[supplied by OMIM]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: VANGL2