Recombinant Human UTP23 His Protein

SDS-Page: UTP23 Protein [NBP2-22936]

• Reactivity: Hu
• Applications: PAGE
• Concentration: 0.5 mg/ml

Recombinant Human UTP23 His Protein Summary

• Description: A recombinant protein with a N-Terminal His-tag and corresponding to the amino acids 1-249 of Human UTP23
  
  

  Source: E.coli

  Amino Acid Sequence: MGSSHHHHHH SSGLVPRGSH MGSMKITRQK HAKKHLGFFR NNFGVREPYQ ILLDGTFCQA ALRGRIQLRE QLPRYLMGET QLCTTRCVLK ELETLGKDLY GAKLIAQKCQ VRNCPHFKNA VSGSECLLSM VEEGNPHHYF VATQDQNLSV KVKKKPGVPL MFIIQNTMVL DKPSPKTIAF VKAVESGQLV SVHEKESIKH LKEEQGLVKN TEQSRRKKRK KISGPNPLSC LKKKKKAPDT QSSASEKKRK RKRIRNRSNP KVLSEKQNAE GE

• Source: E. coli
• Protein/Peptide Type: Recombinant Protein
• Gene: UTP23
• Purity: >90%, by SDS-PAGE

Applications/Dilutions

• Dilutions:
  • SDS-Page
• Theoretical MW: 30.8 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: 20 mM Tris-HCl buffer (pH 8.0), 0.2 M NaCl, 20% glycerol, 1 mM DTT
• Preservative: No Preservative
• Concentration: 0.5 mg/ml
• Purity: >90%, by SDS-PAGE

Alternate Names for Recombinant Human UTP23 His Protein

• C8orf53
• chromosome 8 open reading frame 53
• MGC14595
• rRNA-processing protein UTP23 homolog
• UTP23, small subunit (SSU) processome component, homolog (yeast)

Background

rRNA-processing protein UTP23 homolog, also known as UTP23, is a small subunit (SSU) processome component. The SSU processome is a complex involved in ribosome biogenesis and is required for pre-18S rRNA maturation. UTP23 is required for the first three cleavage steps in 18S rRNA maturation. In addition, single-point mutations in the conserved putative active site of Utp24 but not Utp23 abrogate its function in ribosome biogenesis. Recombinant human UTP23 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

Bioinformatics

• Gene Symbol: UTP23