USP37 Antibody

Western Blot: USP37 Antibody [NB110-40709] - Detection of Human USP37 on HeLa whole cell lysate using NB110-40709. USP37 was also immunoprecipitated by rabbit anti-USP37 antibody NB110-40696.

Immunohistochemistry: USP37 Antibody [NB110-40709] - Sample: FFPE section of human non-small cell lung cancer. Antibody: Affinity purified rabbit anti- USP37 used at a dilution of 1:200 (1ug/ml). Detection: DAB

• Reactivity: Hu
• Applications: WB, IHC, IP
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Concentration: 0.2 mg/ml

USP37 Antibody Summary

• Description: Novus Biologicals Rabbit USP37 Antibody (NB110-40709) is a polyclonal antibody validated for use in IHC, WB and IP. Anti-USP37 Antibody: Cited in 2 publications. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: The immunogen recognized by this antibody maps to a region between residue 930 and the C-terminus (residue 979) of human Ubiquitin Specific Peptidase 37 using the numbering given in entry NP_065986.1 (GeneID 57695).
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: USP37
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry 1:100 - 1:500
  • Immunohistochemistry-Paraffin 1:10-1:500
  • Immunoprecipitation 2-5 ug/mg lysate
  • Western Blot 1:2000-1:10000
• Application Notes: Epitope retrieval with Tris-EDTA pH9.0 is recommended for FFPE tissue sections.
• Control:

  USP37 Overexpression Lysate

Packaging, Storage & Formulations

• Storage: Store at 4C. Do not freeze.
• Buffer: TBS and 0.1% BSA
• Preservative: 0.09% Sodium Azide
• Concentration: 0.2 mg/ml
• Purity: Immunogen affinity purified

Alternate Names for USP37 Antibody

• Deubiquitinating enzyme 37
• EC 3.1.2.15
• EC 3.4.19.12
• KIAA1594tmp_locus_50
• MGC117261
• ubiquitin carboxyl-terminal hydrolase 37
• ubiquitin specific peptidase 37
• ubiquitin specific protease 37
• ubiquitin thioesterase 37
• Ubiquitin thiolesterase 37
• Ubiquitin-specific-processing protease 37
• USP37

Background

UPS37 is a member of the C19 peptidase family of ubiquitin dependent peptidase proteins. It along with similar family members is believed to participate in the cells ubiquitin-dependent protein catabolic processes.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for USP37 Antibody (NB110-40709)(2)

Publications using NB110-40709

• Chauhan R, Gupta A, Malhotra L et al. Ubiquitin specific peptidase 37 and PCNA interaction promotes osteosarcoma pathogenesis by modulating replication fork progression Journal of translational medicine 2023-04-28 [PMID: 37118828] (IP, Human)
• Das CM, Taylor P, Gireud M et al. The deubiquitylase USP37 links REST to the control of p27 stability and cell proliferation. Oncogene 2012-06-01 [PMID: 22665064]

Bioinformatics

• Gene Symbol: USP37
• Entrez:
  • 57695(Human)
• Uniprot:
  • Q86T82(Human)